Tatyana Golovkina, PhD

Professor of Microbiology
Committee on Genetics, Genomics and Systems Biology
Committee on Microbiology
Research and Scholarly Interests: viruses, bacteria, commensal microbes
Websites: Research Network Profile
Contact: tgolovki@uchicago.edu
Graduate Programs: Genetics, Genomics & Systems Biology, Microbiology, Committee on Immunology, UChicago Biosciences

Golovkina's laboratory studies mechanisms of host-pathogen and host-commensal microbe interactions.

Moscow State University
Moscow, Former USSR
PhD - Biochemistry, Virology
1985

Deficiency in non-classical major histocompatibility class II-like molecule, H2-O confers protection against Staphylococcus aureus in mice.
Deficiency in non-classical major histocompatibility class II-like molecule, H2-O confers protection against Staphylococcus aureus in mice. PLoS Pathog. 2024 Jun; 20(6):e1012306.
PMID: 38843309

The endogenous Mtv8 locus and the immunoglobulin repertoire.
The endogenous Mtv8 locus and the immunoglobulin repertoire. Front Immunol. 2024; 15:1345467.
PMID: 38504980

Microbiota may affect the tumor type but not overall tumor development in two models of heritable cancer.
Microbiota may affect the tumor type but not overall tumor development in two models of heritable cancer. bioRxiv. 2023 Oct 12.
PMID: 37873087

A single dominant locus restricts retrovirus replication in YBR/Ei mice.
A single dominant locus restricts retrovirus replication in YBR/Ei mice. J Virol. 2023 08 31; 97(8):e0068523.
PMID: 37578238

Retroviral Infection and Commensal Bacteria Dependently Alter the Metabolomic Profile in a Sterile Organ.
Retroviral Infection and Commensal Bacteria Dependently Alter the Metabolomic Profile in a Sterile Organ. Viruses. 2023 01 29; 15(2).
PMID: 36851600

Retroviral infection and commensal bacteria dependently alter the metabolomic profile in a sterile organ.
Retroviral infection and commensal bacteria dependently alter the metabolomic profile in a sterile organ. bioRxiv. 2023 Jan 11.
PMID: 36711645

Gut commensal bacteria enhance pathogenesis of a tumorigenic murine retrovirus.
Gut commensal bacteria enhance pathogenesis of a tumorigenic murine retrovirus. Cell Rep. 2022 09 13; 40(11):111341.
PMID: 36103821

Mouse Homologue of Human HLA-DO Does Not Preempt Autoimmunity but Controls Murine Gammaherpesvirus MHV68.
Mouse Homologue of Human HLA-DO Does Not Preempt Autoimmunity but Controls Murine Gammaherpesvirus MHV68. J Immunol. 2021 12 15; 207(12):2944-2951.
PMID: 34810225

MHC Class II Presentation Is Affected by Polymorphism in the H2-Ob Gene and Additional Loci.
MHC Class II Presentation Is Affected by Polymorphism in the H2-Ob Gene and Additional Loci. J Immunol. 2021 07 01; 207(1):5-14.
PMID: 34135064

Genetic Control of Neonatal Immune Tolerance to an Exogenous Retrovirus.
Genetic Control of Neonatal Immune Tolerance to an Exogenous Retrovirus. J Virol. 2020 11 23; 94(24).
PMID: 32999021

View All Publications

The KT Jeang Retrovirology prize
University of Chicago
2020

Fellow of American Association for the Advancement of Science
2019

Fellow of the American Academy of Microbiology
2018

Cancer Research Institute (CRI) 2000 Hillsdale Fund, Inc. Greensboro, N.C.
2000

Oliver and Jennie Donaldson Charitable Trust
2000

V Foundation Scholar
1997

Cancer Research Institute Postdoctoral Fellowship Award
1993 - 1995

Prize of All-Union Young Scientists competition (together with S.V. Litvinov)
1987