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  4. Jeffrey Hubbell

Jeffrey Hubbell

Barry L. Maclean Professor
jhubbell@uchicago.edu
Biosciences Graduate Program Association
Publications

  1. Treatment of peanut allergy and colitis in mice via the intestinal release of butyrate from polymeric micelles. Nat Biomed Eng. 2023 Jan; 7(1):38-55. View in: PubMed

  2. Tumor Cell-Surface Binding of Immune Stimulating Polymeric Glyco-Adjuvant via Cysteine-Reactive Pyridyl Disulfide Promotes Antitumor Immunity. ACS Cent Sci. 2022 Oct 26; 8(10):1435-1446. View in: PubMed

  3. Severe COVID-19 induces autoantibodies against angiotensin II that correlate with blood pressure dysregulation and disease severity. Sci Adv. 2022 10 07; 8(40):eabn3777. View in: PubMed

  4. Therapeutic arteriogenesis by factor-decorated fibrin matrices promotes wound healing in diabetic mice. J Tissue Eng. 2022 Jan-Dec; 13:20417314221119615. View in: PubMed

  5. Immunostimulatory Polymers as Adjuvants, Immunotherapies, and Delivery Systems. Macromolecules. 2022 Aug 23; 55(16):6913-6937. View in: PubMed

  6. Robust coupling of angiogenesis and osteogenesis by VEGF-decorated matrices for bone regeneration. Acta Biomater. 2022 09 01; 149:111-125. View in: PubMed

  7. Therapeutic use of a2-antiplasmin as an antifibrinolytic and hemostatic agent in surgery and regenerative medicine. NPJ Regen Med. 2022 Jun 30; 7(1):34. View in: PubMed

  8. Masking the immunotoxicity of interleukin-12 by fusing it with a domain of its receptor via a tumour-protease-cleavable linker. Nat Biomed Eng. 2022 07; 6(7):819-829. View in: PubMed

  9. Kidney repair and regeneration: perspectives of the NIDDK (Re)Building a Kidney consortium. Kidney Int. 2022 05; 101(5):845-853. View in: PubMed

  10. VEGF-A, PDGF-BB and HB-EGF engineered for promiscuous super affinity to the extracellular matrix improve wound healing in a model of type 1 diabetes. NPJ Regen Med. 2021 Nov 18; 6(1):76. View in: PubMed

  11. SARS-CoV-2 infection induces cross-reactive autoantibodies against angiotensin II. medRxiv. 2021 Nov 02. View in: PubMed

  12. Overcoming transport barriers to immunotherapy. Drug Deliv Transl Res. 2021 12; 11(6):2273-2275. View in: PubMed

  13. Generation of potent cellular and humoral immunity against SARS-CoV-2 antigens via conjugation to a polymeric glyco-adjuvant. Biomaterials. 2021 11; 278:121159. View in: PubMed

  14. Lymph Node-Targeted Synthetically Glycosylated Antigen Leads to Antigen-Specific Immunological Tolerance. Front Immunol. 2021; 12:714842. View in: PubMed

  15. Polymersomes Decorated with the SARS-CoV-2 Spike Protein Receptor-Binding Domain Elicit Robust Humoral and Cellular Immunity. ACS Cent Sci. 2021 Aug 25; 7(8):1368-1380. View in: PubMed

  16. Robust Angiogenesis and Arteriogenesis in the Skin of Diabetic Mice by Transient Delivery of Engineered VEGF and PDGF-BB Proteins in Fibrin Hydrogels. Front Bioeng Biotechnol. 2021; 9:688467. View in: PubMed

  17. Immunoengineering approaches for cytokine therapy. Am J Physiol Cell Physiol. 2021 08 01; 321(2):C369-C383. View in: PubMed

  18. Engineered bridge protein with dual affinity for bone morphogenetic protein-2 and collagen enhances bone regeneration for spinal fusion. Sci Adv. 2021 06; 7(24). View in: PubMed

  19. Polymersomes decorated with SARS-CoV-2 spike protein receptor binding domain elicit robust humoral and cellular immunity. bioRxiv. 2021 Apr 08. View in: PubMed

  20. Lymphangiogenesis-inducing vaccines elicit potent and long-lasting T cell immunity against melanomas. Sci Adv. 2021 03; 7(13). View in: PubMed

  21. Soluble N-Acetylgalactosamine-Modified Antigens Enhance Hepatocyte-Dependent Antigen Cross-Presentation and Result in Antigen-Specific CD8+ T Cell Tolerance Development. Front Immunol. 2021; 12:555095. View in: PubMed

  22. Persistent antigen exposure via the eryptotic pathway drives terminal T cell dysfunction. Sci Immunol. 2021 02 26; 6(56). View in: PubMed

  23. A Cationic Micelle Complex Improves CD8+ T Cell Responses in Vaccination Against Unmodified Protein Antigen. ACS Biomater Sci Eng. 2016 Feb 08; 2(2):231-240. View in: PubMed

  24. Suppression of Rheumatoid Arthritis by Enhanced Lymph Node Trafficking of Engineered Interleukin-10 in Murine Models. Arthritis Rheumatol. 2021 05; 73(5):769-778. View in: PubMed

  25. Publisher Correction: Prolonged residence of an albumin-IL-4 fusion protein in secondary lymphoid organs ameliorates experimental autoimmune encephalomyelitis. Nat Biomed Eng. 2020 Nov; 4(11):1117. View in: PubMed

  26. Prolonged residence of an albumin-IL-4 fusion protein in secondary lymphoid organs ameliorates experimental autoimmune encephalomyelitis. Nat Biomed Eng. 2021 05; 5(5):387-398. View in: PubMed

  27. Thermally-induced glass formation from hydrogel nanoparticles. Soft Matter. 2006 Nov 15; 2(12):1067-1075. View in: PubMed

  28. An optimized antigen-protein fusion. Nat Biomed Eng. 2020 06; 4(6):583-584. View in: PubMed

  29. Collagen-binding IL-12 enhances tumour inflammation and drives the complete remission of established immunologically cold mouse tumours. Nat Biomed Eng. 2020 05; 4(5):531-543. View in: PubMed

  30. Engineering Targeting Materials for Therapeutic Cancer Vaccines. Front Bioeng Biotechnol. 2020; 8:19. View in: PubMed

  31. Conferring extracellular matrix affinity enhances local therapeutic efficacy of anti-TNF-a antibody in a murine model of rheumatoid arthritis. Arthritis Res Ther. 2019 12 23; 21(1):298. View in: PubMed

  32. Recruitment of CD103+ dendritic cells via tumor-targeted chemokine delivery enhances efficacy of checkpoint inhibitor immunotherapy. Sci Adv. 2019 12; 5(12):eaay1357. View in: PubMed

  33. Targeting inflammatory sites through collagen affinity enhances the therapeutic efficacy of anti-inflammatory antibodies. Sci Adv. 2019 11; 5(11):eaay1971. View in: PubMed

  34. Growth factors with enhanced syndecan binding generate tonic signalling and promote tissue healing. Nat Biomed Eng. 2020 04; 4(4):463-475. View in: PubMed

  35. Synthetic 3D PEG-Anisogel Tailored with Fibronectin Fragments Induce Aligned Nerve Extension. Biomacromolecules. 2019 11 11; 20(11):4075-4087. View in: PubMed

  36. Engineered collagen-binding serum albumin as a drug conjugate carrier for cancer therapy. Sci Adv. 2019 08; 5(8):eaaw6081. View in: PubMed

  37. Synthetically glycosylated antigens induce antigen-specific tolerance and prevent the onset of diabetes. Nat Biomed Eng. 2019 10; 3(10):817-829. View in: PubMed

  38. The heparin binding domain of von Willebrand factor binds to growth factors and promotes angiogenesis in wound healing. Blood. 2019 06 13; 133(24):2559-2569. View in: PubMed

  39. Targeted antibody and cytokine cancer immunotherapies through collagen affinity. Sci Transl Med. 2019 04 10; 11(487). View in: PubMed

  40. A Bioinspired Scaffold with Anti-Inflammatory Magnesium Hydroxide and Decellularized Extracellular Matrix for Renal Tissue Regeneration. ACS Cent Sci. 2019 Mar 27; 5(3):458-467. View in: PubMed

  41. A bioactive injectable bulking material; a potential therapeutic approach for stress urinary incontinence. Biomaterials. 2019 06; 206:41-48. View in: PubMed

  42. Combination of Synthetic Long Peptides and XCL1 Fusion Proteins Results in Superior Tumor Control. Front Immunol. 2019; 10:294. View in: PubMed

  43. Quantitative intrinsic auto-cathodoluminescence can resolve spectral signatures of tissue-isolated collagen extracellular matrix. Commun Biol. 2019; 2:69. View in: PubMed

  44. Trojan horses for immunotherapy. Nat Nanotechnol. 2019 03; 14(3):196-197. View in: PubMed

  45. Antigens reversibly conjugated to a polymeric glyco-adjuvant induce protective humoral and cellular immunity. Nat Mater. 2019 02; 18(2):175-185. View in: PubMed

  46. Improving Efficacy and Safety of Agonistic Anti-CD40 Antibody Through Extracellular Matrix Affinity. Mol Cancer Ther. 2018 11; 17(11):2399-2411. View in: PubMed

  47. Fiber density of collagen grafts impacts rabbit urethral regeneration. Sci Rep. 2018 07 03; 8(1):10057. View in: PubMed

  48. Laminin heparin-binding peptides bind to several growth factors and enhance diabetic wound healing. Nat Commun. 2018 06 04; 9(1):2163. View in: PubMed

  49. Modified Magnesium Hydroxide Nanoparticles Inhibit the Inflammatory Response to Biodegradable Poly(lactide- co-glycolide) Implants. ACS Nano. 2018 07 24; 12(7):6917-6925. View in: PubMed

  50. Adaptive enhanced sampling by force-biasing using neural networks. J Chem Phys. 2018 Apr 07; 148(13):134108. View in: PubMed

  51. Microfluidic production of bioactive fibrin micro-beads embedded in crosslinked collagen used as an injectable bulking agent for urinary incontinence treatment. Acta Biomater. 2018 02; 67:156-166. View in: PubMed

  52. Matrix-binding checkpoint immunotherapies enhance antitumor efficacy and reduce adverse events. Sci Transl Med. 2017 Nov 08; 9(415). View in: PubMed

  53. Immunoisolation of murine islet allografts in vascularized sites through conformal coating with polyethylene glycol. Am J Transplant. 2018 03; 18(3):590-603. View in: PubMed

  54. Oxidation-sensitive polymersomes as vaccine nanocarriers enhance humoral responses against Lassa virus envelope glycoprotein. Virology. 2017 12; 512:161-171. View in: PubMed

  55. Bioengineering strategies for inducing tolerance in autoimmune diabetes. Adv Drug Deliv Rev. 2017 05 15; 114:256-265. View in: PubMed

  56. Corrigendum: Advances in pancreatic islet monolayer culture on glass surfaces enable super-resolution microscopy and insights into beta cell ciliogenesis and proliferation. Sci Rep. 2017 05 09; 7:46801. View in: PubMed

  57. Human Kunitz-type protease inhibitor engineered for enhanced matrix retention extends longevity of fibrin biomaterials. Biomaterials. 2017 Aug; 135:1-9. View in: PubMed

  58. Local induction of lymphangiogenesis with engineered fibrin-binding VEGF-C promotes wound healing by increasing immune cell trafficking and matrix remodeling. Biomaterials. 2017 07; 131:160-175. View in: PubMed

  59. Vaccine nanocarriers: Coupling intracellular pathways and cellular biodistribution to control CD4 vs CD8 T cell responses. Biomaterials. 2017 07; 132:48-58. View in: PubMed

  60. Advances in pancreatic islet monolayer culture on glass surfaces enable super-resolution microscopy and insights into beta cell ciliogenesis and proliferation. Sci Rep. 2017 04 12; 7:45961. View in: PubMed

  61. Toll-like receptor 8 agonist nanoparticles mimic immunomodulating effects of the live BCG vaccine and enhance neonatal innate and adaptive immune responses. J Allergy Clin Immunol. 2017 Nov; 140(5):1339-1350. View in: PubMed

  62. (Re)Building a Kidney. J Am Soc Nephrol. 2017 May; 28(5):1370-1378. View in: PubMed

  63. Primary Human and Rat ?-Cells Release the Intracellular Autoantigens GAD65, IA-2, and Proinsulin in Exosomes Together With Cytokine-Induced Enhancers of Immunity. Diabetes. 2017 02; 66(2):460-473. View in: PubMed

  64. Difference in suitable mechanical properties of three-dimensional, synthetic scaffolds for self-renewing mouse embryonic stem cells of different genetic backgrounds. J Biomed Mater Res B Appl Biomater. 2017 Nov; 105(8):2261-2268. View in: PubMed

  65. Engineered acellular collagen scaffold for endogenous cell guidance, a novel approach in urethral regeneration. Acta Biomater. 2016 10 01; 43:208-217. View in: PubMed

  66. IGF-1-containing multi-layered collagen-fibrin hybrid scaffolds for bladder tissue engineering. Acta Biomater. 2016 09 01; 41:75-85. View in: PubMed

  67. Aberrant Accumulation of the Diabetes Autoantigen GAD65 in Golgi Membranes in Conditions of ER Stress and Autoimmunity. Diabetes. 2016 09; 65(9):2686-99. View in: PubMed

  68. Fibronectin EDA and CpG synergize to enhance antigen-specific Th1 and cytotoxic responses. Vaccine. 2016 05 05; 34(21):2453-2459. View in: PubMed

  69. Hollow Mesoporous Plasmonic Nanoshells for Enhanced Solar Vapor Generation. Nano Lett. 2016 Apr 13; 16(4):2159-67. View in: PubMed

  70. TLR-3 stimulation improves anti-tumor immunity elicited by dendritic cell exosome-based vaccines in a murine model of melanoma. Sci Rep. 2015 Dec 03; 5:17622. View in: PubMed

  71. Engineered binding to erythrocytes induces immunological tolerance to E. coli asparaginase. Sci Adv. 2015 Jul; 1(6):e1500112. View in: PubMed

  72. Engineering growth factors for regenerative medicine applications. Acta Biomater. 2016 Jan; 30:1-12. View in: PubMed

  73. Memory of tolerance and induction of regulatory T cells by erythrocyte-targeted antigens. Sci Rep. 2015 Oct 29; 5:15907. View in: PubMed

  74. Kinetics of Ultrasonic Drug Delivery from Targeted Micelles. J Nanosci Nanotechnol. 2015 Mar; 15(3):2099-104. View in: PubMed

  75. Nanoparticle conjugation enhances the immunomodulatory effects of intranasally delivered CpG in house dust mite-allergic mice. Sci Rep. 2015 Sep 21; 5:14274. View in: PubMed

  76. Extracellular Matrix-Inspired Growth Factor Delivery Systems for Skin Wound Healing. Adv Wound Care (New Rochelle). 2015 Aug 01; 4(8):479-489. View in: PubMed

  77. Engineering antigen-specific immunological tolerance. Curr Opin Immunol. 2015 Aug; 35:80-8. View in: PubMed

  78. Crystalline Oligo(ethylene sulfide) Domains Define Highly Stable Supramolecular Block Copolymer Assemblies. ACS Nano. 2015 Jul 28; 9(7):6872-81. View in: PubMed

  79. Tubular Compressed Collagen Scaffolds for Ureteral Tissue Engineering in a Flow Bioreactor System. Tissue Eng Part A. 2015 Sep; 21(17-18):2334-45. View in: PubMed

  80. Prescription for a pharmacyte. Sci Transl Med. 2015 Jun 10; 7(291):291fs23. View in: PubMed

  81. 6-Thioguanine-loaded polymeric micelles deplete myeloid-derived suppressor cells and enhance the efficacy of T cell immunotherapy in tumor-bearing mice. Cancer Immunol Immunother. 2015 Aug; 64(8):1033-46. View in: PubMed

  82. Extracellular matrix-inspired growth factor delivery systems for bone regeneration. Adv Drug Deliv Rev. 2015 Nov 01; 94:41-52. View in: PubMed

  83. Extracellular matrix and growth factor engineering for controlled angiogenesis in regenerative medicine. Front Bioeng Biotechnol. 2015; 3:45. View in: PubMed

  84. Fibrin gels engineered with pro-angiogenic growth factors promote engraftment of pancreatic islets in extrahepatic sites in mice. Biotechnol Bioeng. 2015 Sep; 112(9):1916-26. View in: PubMed

  85. The TLR4 agonist fibronectin extra domain A is cryptic, exposed by elastase-2; use in a fibrin matrix cancer vaccine. Sci Rep. 2015 Feb 24; 5:8569. View in: PubMed

  86. Molecularly engineered self-assembling membranes for cell-mediated degradation. Adv Healthc Mater. 2015 Mar 11; 4(4):602-12. View in: PubMed

  87. Overcoming immunological barriers in regenerative medicine. Nat Biotechnol. 2014 Aug; 32(8):786-94. View in: PubMed

  88. Device design and materials optimization of conformal coating for islets of Langerhans. Proc Natl Acad Sci U S A. 2014 Jul 22; 111(29):10514-9. View in: PubMed

  89. Bioluminescent and micro-computed tomography imaging of bone repair induced by fibrin-binding growth factors. Acta Biomater. 2014 Oct; 10(10):4377-89. View in: PubMed

  90. Enhancing efficacy of anticancer vaccines by targeted delivery to tumor-draining lymph nodes. Cancer Immunol Res. 2014 May; 2(5):436-47. View in: PubMed

  91. Long-lasting fibrin matrices ensure stable and functional angiogenesis by highly tunable, sustained delivery of recombinant VEGF164. Proc Natl Acad Sci U S A. 2014 May 13; 111(19):6952-7. View in: PubMed

  92. Clonal, self-renewing and differentiating human and porcine urothelial cells, a novel stem cell population. PLoS One. 2014; 9(2):e90006. View in: PubMed

  93. Growth factors engineered for super-affinity to the extracellular matrix enhance tissue healing. Science. 2014 Feb 21; 343(6173):885-8. View in: PubMed

  94. Culture of preantral follicles in poly(ethylene) glycol-based, three-dimensional hydrogel: a relationship between swelling ratio and follicular developments. J Tissue Eng Regen Med. 2015 Mar; 9(3):319-23. View in: PubMed

  95. Nanoparticle conjugation of CpG enhances adjuvancy for cellular immunity and memory recall at low dose. Proc Natl Acad Sci U S A. 2013 Dec 03; 110(49):19902-7. View in: PubMed

  96. Fibronectin binding modulates CXCL11 activity and facilitates wound healing. PLoS One. 2013; 8(10):e79610. View in: PubMed

  97. Translating materials design to the clinic. Nat Mater. 2013 Nov; 12(11):963-6. View in: PubMed

  98. Targeting the tumor-draining lymph node with adjuvanted nanoparticles reshapes the anti-tumor immune response. Biomaterials. 2014 Jan; 35(2):814-24. View in: PubMed

  99. In situ cell manipulation through enzymatic hydrogel photopatterning. Nat Mater. 2013 Nov; 12(11):1072-8. View in: PubMed

  100. VEGFR-3 neutralization inhibits ovarian lymphangiogenesis, follicle maturation, and murine pregnancy. Am J Pathol. 2013 Nov; 183(5):1596-1607. View in: PubMed

  101. Tissue, cell and engineering. Curr Opin Biotechnol. 2013 Oct; 24(5):827-9. View in: PubMed

  102. Preparation of well-defined ibuprofen prodrug micelles by RAFT polymerization. Biomacromolecules. 2013 Sep 09; 14(9):3314-20. View in: PubMed

  103. Proangiogenic hydrogels within macroporous scaffolds enhance islet engraftment in an extrahepatic site. Tissue Eng Part A. 2013 Dec; 19(23-24):2544-52. View in: PubMed

  104. The promotion of endothelial cell attachment and spreading using FNIII10 fused to VEGF-A165. Biomaterials. 2013 Aug; 34(24):5958-68. View in: PubMed

  105. Proteolytic processing regulates placental growth factor activities. J Biol Chem. 2013 Jun 21; 288(25):17976-89. View in: PubMed

  106. Tenascin C promiscuously binds growth factors via its fifth fibronectin type III-like domain. PLoS One. 2013; 8(4):e62076. View in: PubMed

  107. Peripherally administered nanoparticles target monocytic myeloid cells, secondary lymphoid organs and tumors in mice. PLoS One. 2013; 8(4):e61646. View in: PubMed

  108. Heparin-binding domain of fibrin(ogen) binds growth factors and promotes tissue repair when incorporated within a synthetic matrix. Proc Natl Acad Sci U S A. 2013 Mar 19; 110(12):4563-8. View in: PubMed

  109. Tunable T cell immunity towards a protein antigen using polymersomes vs. solid-core nanoparticles. Biomaterials. 2013 Jun; 34(17):4339-46. View in: PubMed

  110. A high-throughput nanoimmunoassay chip applied to large-scale vaccine adjuvant screening. Integr Biol (Camb). 2013 Apr; 5(4):650-8. View in: PubMed

  111. A feeder-free, defined three-dimensional polyethylene glycol-based extracellular matrix niche for culture of human embryonic stem cells. Biomaterials. 2013 May; 34(14):3571-80. View in: PubMed

  112. Engineering antigens for in situ erythrocyte binding induces T-cell deletion. Proc Natl Acad Sci U S A. 2013 Jan 02; 110(1):E60-8. View in: PubMed

  113. Sorting live stem cells based on Sox2 mRNA expression. PLoS One. 2012; 7(11):e49874. View in: PubMed

  114. Embryonic stem cell-based cardiopatches improve cardiac function in infarcted rats. Stem Cells Transl Med. 2012 Mar; 1(3):248-60. View in: PubMed

  115. Engineering the regenerative microenvironment with biomaterials. Adv Healthc Mater. 2013 Jan; 2(1):57-71. View in: PubMed

  116. Nanoparticle size influences the magnitude and quality of mucosal immune responses after intranasal immunization. Vaccine. 2012 Dec 14; 30(52):7541-6. View in: PubMed

  117. Improving the osteogenic potential of BMP-2 with hyaluronic acid hydrogel modified with integrin-specific fibronectin fragment. Biomaterials. 2013 Jan; 34(3):704-12. View in: PubMed

  118. Long-term maintenance of mouse embryonic stem cell pluripotency by manipulating integrin signaling within 3D scaffolds without active Stat3. Biomaterials. 2012 Dec; 33(35):8934-42. View in: PubMed

  119. Reduction-sensitive tioguanine prodrug micelles. Mol Pharm. 2012 Oct 01; 9(10):2812-8. View in: PubMed

  120. Engineering approaches to immunotherapy. Sci Transl Med. 2012 Aug 22; 4(148):148rv9. View in: PubMed

  121. Precision intracellular delivery based on optofluidic polymersome rupture. ACS Nano. 2012 Sep 25; 6(9):7850-7. View in: PubMed

  122. Chemistry. Nanomaterials for drug delivery. Science. 2012 Jul 20; 337(6092):303-5. View in: PubMed

  123. Investigating the acoustic release of doxorubicin from targeted micelles. Colloids Surf B Biointerfaces. 2013 Jan 01; 101:153-5. View in: PubMed

  124. In-vivo performance of high-density collagen gel tubes for urethral regeneration in a rabbit model. Biomaterials. 2012 Oct; 33(30):7447-55. View in: PubMed

  125. Polymer micelles with pyridyl disulfide-coupled antigen travel through lymphatics and show enhanced cellular responses following immunization. Acta Biomater. 2012 Sep; 8(9):3210-7. View in: PubMed

  126. Dendritic cell activation and T cell priming with adjuvant- and antigen-loaded oxidation-sensitive polymersomes. Biomaterials. 2012 Sep; 33(26):6211-9. View in: PubMed

  127. Size- and charge-dependent non-specific uptake of PEGylated nanoparticles by macrophages. Int J Nanomedicine. 2012; 7:799-813. View in: PubMed

  128. Drug development: longer-lived proteins. Chem Soc Rev. 2012 Apr 07; 41(7):2686-95. View in: PubMed

  129. Twenty-third annual Pezcoller Symposium: engineering influences in cancer research. Cancer Res. 2012 Feb 15; 72(4):841-4. View in: PubMed

  130. Engineered insulin-like growth factor-1 for improved smooth muscle regeneration. Biomaterials. 2012 Jan; 33(2):494-503. View in: PubMed

  131. Nanoparticle conjugation of antigen enhances cytotoxic T-cell responses in pulmonary vaccination. Proc Natl Acad Sci U S A. 2011 Nov 01; 108(44):E989-97. View in: PubMed

  132. PEG-b-PPS-b-PEI micelles and PEG-b-PPS/PEG-b-PPS-b-PEI mixed micelles as non-viral vectors for plasmid DNA: tumor immunotoxicity in B16F10 melanoma. Biomaterials. 2011 Dec; 32(36):9839-47. View in: PubMed

  133. Engineering the growth factor microenvironment with fibronectin domains to promote wound and bone tissue healing. Sci Transl Med. 2011 Sep 14; 3(100):100ra89. View in: PubMed

  134. Toxicity and exposure of an adenovirus containing human interferon alpha-2b following intracystic administration in cynomolgus monkeys. Gene Ther. 2012 Jul; 19(7):742-51. View in: PubMed

  135. Nano-sized drug-loaded micelles deliver payload to lymph node immune cells and prolong allograft survival. J Control Release. 2011 Dec 10; 156(2):154-60. View in: PubMed

  136. Nanoparticle conjugation and pulmonary delivery enhance the protective efficacy of Ag85B and CpG against tuberculosis. Vaccine. 2011 Sep 16; 29(40):6959-66. View in: PubMed

  137. Extracellular matrix in angiogenesis: dynamic structures with translational potential. Exp Dermatol. 2011 Jul; 20(7):605-13. View in: PubMed

  138. A collagen-poly(lactic acid-co-?-caprolactone) hybrid scaffold for bladder tissue regeneration. Biomaterials. 2011 Jun; 32(16):3969-76. View in: PubMed

  139. In situ photopolymerized hydrogels for vascular and peritoneal wound healing. Methods Mol Med. 1999; 18:85-100. View in: PubMed

  140. Enzymatic- and temperature-sensitive controlled release of ultrasmall superparamagnetic iron oxides (USPIOs). J Nanobiotechnology. 2011 Feb 27; 9:7. View in: PubMed

  141. Engineering complement activation on polypropylene sulfide vaccine nanoparticles. Biomaterials. 2011 Mar; 32(8):2194-203. View in: PubMed

  142. Biocompatible dispersions of carbon nanotubes: a potential tool for intracellular transport of anticancer drugs. Nanoscale. 2011 Mar; 3(3):925-8. View in: PubMed

  143. Analytical ultracentrifugation to support the development of biomaterials and biomedical devices. Methods. 2011 May; 54(1):92-100. View in: PubMed

  144. Carbon monoxide-releasing micelles for immunotherapy. J Am Chem Soc. 2010 Dec 29; 132(51):18273-80. View in: PubMed

  145. PPS nanoparticles as versatile delivery system to induce systemic and broad mucosal immunity after intranasal administration. Vaccine. 2011 Jan 17; 29(4):804-12. View in: PubMed

  146. High-density collagen gel tubes as a matrix for primary human bladder smooth muscle cells. Biomaterials. 2011 Feb; 32(6):1543-8. View in: PubMed

  147. SPARC-derived protease substrates to enhance the plasmin sensitivity of molecularly engineered PEG hydrogels. Biomaterials. 2011 Feb; 32(5):1301-10. View in: PubMed

  148. Human embryonic stem cell-derived microvascular grafts for cardiac tissue preservation after myocardial infarction. Biomaterials. 2011 Feb; 32(4):1102-9. View in: PubMed

  149. Drug development: Longer-lived proteins. Nature. 2010 Oct 28; 467(7319):1051-2. View in: PubMed

  150. Antigen delivery to dendritic cells by poly(propylene sulfide) nanoparticles with disulfide conjugated peptides: Cross-presentation and T cell activation. Vaccine. 2010 Nov 23; 28(50):7897-906. View in: PubMed

  151. Engineered aprotinin for improved stability of fibrin biomaterials. Biomaterials. 2011 Jan; 32(2):430-8. View in: PubMed

  152. Improving protein pharmacokinetics by engineering erythrocyte affinity. Mol Pharm. 2010 Dec 06; 7(6):2141-7. View in: PubMed

  153. Dynamic perspective on the function of thermoresponsive nanopores from in situ AFM and ATR-IR investigations. Langmuir. 2010 Oct 05; 26(19):15356-65. View in: PubMed

  154. The effect of matrix characteristics on fibroblast proliferation in 3D gels. Biomaterials. 2010 Nov; 31(32):8454-64. View in: PubMed

  155. The 12th-14th type III repeats of fibronectin function as a highly promiscuous growth factor-binding domain. FASEB J. 2010 Dec; 24(12):4711-21. View in: PubMed

  156. Enhanced proteolytic degradation of molecularly engineered PEG hydrogels in response to MMP-1 and MMP-2. Biomaterials. 2010 Oct; 31(30):7836-45. View in: PubMed

  157. Controlled release nanoparticle-embedded coatings reduce the tissue reaction to neuroprostheses. J Control Release. 2010 Aug 03; 145(3):196-202. View in: PubMed

  158. Synthesis of pyridyl disulfide-functionalized nanoparticles for conjugating thiol-containing small molecules, peptides, and proteins. Bioconjug Chem. 2010 Apr 21; 21(4):653-62. View in: PubMed

  159. In vivo study of an injectable poly(acrylonitrile)-based hydrogel paste as a bulking agent for the treatment of urinary incontinence. Biomaterials. 2010 Jun; 31(17):4613-9. View in: PubMed

  160. Microfluidic assays for DNA manipulation based on a block copolymer immobilization strategy. Biomacromolecules. 2010 Mar 08; 11(3):827-31. View in: PubMed

  161. Integration column: biofunctional polymeric nanoparticles for spatio-temporal control of drug delivery and biomedical applications. Integr Biol (Camb). 2009 Jul; 1(7):446-51. View in: PubMed

  162. In vitro uptake of amphiphilic, hydrogel nanoparticles by J774A.1 cells. J Biomed Mater Res A. 2010 Jun 15; 93(4):1557-65. View in: PubMed

  163. Materials engineering for immunomodulation. Nature. 2009 Nov 26; 462(7272):449-60. View in: PubMed

  164. Engineering integrin signaling for promoting embryonic stem cell self-renewal in a precisely defined niche. Biomaterials. 2010 Feb; 31(6):1219-26. View in: PubMed

  165. A facile strategy for the modification of polyethylene substrates with non-fouling, bioactive poly(poly(ethylene glycol) methacrylate) brushes. Macromol Biosci. 2010 Jan 11; 10(1):101-8. View in: PubMed

  166. Fabrication of nanopore arrays and ultrathin silicon nitride membranes by block-copolymer-assisted lithography. Nanotechnology. 2009 Dec 02; 20(48):485303. View in: PubMed

  167. Compressed collagen gel: a novel scaffold for human bladder cells. J Tissue Eng Regen Med. 2010 Feb; 4(2):123-30. View in: PubMed

  168. Micelles for delivery of nitric oxide. J Am Chem Soc. 2009 Oct 14; 131(40):14413-8. View in: PubMed

  169. Aggregation behavior of poly(ethylene glycol-bl-propylene sulfide) di- and triblock copolymers in aqueous solution. Langmuir. 2009 Oct 06; 25(19):11328-35. View in: PubMed

  170. Biomimetic PEG hydrogels crosslinked with minimal plasmin-sensitive tri-amino acid peptides. J Biomed Mater Res A. 2010 Jun 01; 93(3):870-7. View in: PubMed

  171. A novel method for the encapsulation of biomolecules into polymersomes via direct hydration. Langmuir. 2009 Aug 18; 25(16):9025-9. View in: PubMed

  172. MICROPATTERNING OF GOLD SUBSTRATES BASED ON POLY(PROPYLENE SULFIDE-BL-ETHYLENE GLYCOL), (PPS-PEG) BACKGROUND PASSIVATION AND THE MOLECULAR-ASSEMBLY PATTERNING BY LIFT-OFF (MAPL) TECHNIQUE. Surf Sci. 2008 Jul 01; 602(13):2305-2310. View in: PubMed

  173. Cell-responsive hydrogel for encapsulation of vascular cells. Biomaterials. 2009 Sep; 30(26):4318-24. View in: PubMed

  174. Porphyrin-based photocatalytic nanolithography: a new fabrication tool for protein arrays. Mol Cell Proteomics. 2009 Aug; 8(8):1823-31. View in: PubMed

  175. Extracellular matrix binding mixed micelles for drug delivery applications. J Control Release. 2009 Jul 20; 137(2):146-51. View in: PubMed

  176. Chemical tethering of motile bacteria to silicon surfaces. Biotechniques. 2009 Mar; 46(3):209-16. View in: PubMed

  177. Bone healing induced by local delivery of an engineered parathyroid hormone prodrug. Biomaterials. 2009 Mar; 30(9):1763-71. View in: PubMed

  178. Phototocatalytic lithography of poly(propylene sulfide) block copolymers: toward high-throughput nanolithography for biomolecular arraying applications. Langmuir. 2009 Jan 20; 25(2):1238-44. View in: PubMed

  179. Controlling integrin specificity and stem cell differentiation in 2D and 3D environments through regulation of fibronectin domain stability. Biomaterials. 2009 Feb; 30(6):1089-97. View in: PubMed

  180. Superparamagnetic nanoparticles as a powerful systems biology characterization tool in the physiological context. Angew Chem Int Ed Engl. 2008; 47(41):7857-60. View in: PubMed

  181. Cellular matrices: Physiology in microfluidics. Nat Mater. 2008 Aug; 7(8):609-10. View in: PubMed

  182. Platelet adhesion to polyurethane blended with polytetramethylene oxide. Biotechnol Bioeng. 1996 Oct 05; 52(1):81-8. View in: PubMed

  183. Modification of islet of langerhans surfaces with immunoprotective poly(ethylene glycol) coatings via interfacial photopolymerization. Biotechnol Bioeng. 1994 Jul; 44(3):383-6. View in: PubMed

  184. Multifunctional poly(ethylene glycol) semi-interpenetrating polymer networks as highly selective adhesive substrates for bioadhesive peptide grafting. Biotechnol Bioeng. 1994 Apr 05; 43(8):772-80. View in: PubMed

  185. Preface: Tissue engineering and cell therapies: II. Biotechnol Bioeng. 1994 Apr 05; 43(8):683. View in: PubMed

  186. Preface. Tissue engineering and cell therapies. Biotechnol Bioeng. 1994 Mar 25; 43(7):541. View in: PubMed

  187. PEG-b-PPS diblock copolymer aggregates for hydrophobic drug solubilization and release: cyclosporin A as an example. Mol Pharm. 2008 Jul-Aug; 5(4):632-42. View in: PubMed

  188. Three-dimensional extracellular matrix-directed cardioprogenitor differentiation: systematic modulation of a synthetic cell-responsive PEG-hydrogel. Biomaterials. 2008 Jun; 29(18):2757-66. View in: PubMed

  189. Porphyrin-based photocatalytic lithography. Langmuir. 2008 May 06; 24(9):5179-84. View in: PubMed

  190. Biofunctional polymer nanoparticles for intra-articular targeting and retention in cartilage. Nat Mater. 2008 Mar; 7(3):248-54. View in: PubMed

  191. Functionalization of polysulfide nanoparticles and their performance as circulating carriers. Biomaterials. 2008 Apr; 29(12):1958-66. View in: PubMed

  192. Dielectrophoresis-based particle exchanger for the manipulation and surface functionalization of particles. Lab Chip. 2008 Feb; 8(2):267-73. View in: PubMed

  193. Lymphatic drainage function and its immunological implications: from dendritic cell homing to vaccine design. Semin Immunol. 2008 Apr; 20(2):147-56. View in: PubMed

  194. The role of actively released fibrin-conjugated VEGF for VEGF receptor 2 gene activation and the enhancement of angiogenesis. Biomaterials. 2008 Apr; 29(11):1720-9. View in: PubMed

  195. Controlled release drug coatings on flexible neural probes. Annu Int Conf IEEE Eng Med Biol Soc. 2007; 2007:6613-6. View in: PubMed

  196. The effect of enzymatically degradable poly(ethylene glycol) hydrogels on smooth muscle cell phenotype. Biomaterials. 2008 Jan; 29(3):314-26. View in: PubMed

  197. Bioluminescence imaging of calvarial bone repair using bone marrow and adipose tissue-derived mesenchymal stem cells. Biomaterials. 2008 Feb; 29(4):427-37. View in: PubMed

  198. Biomolecular hydrogels formed and degraded via site-specific enzymatic reactions. Biomacromolecules. 2007 Oct; 8(10):3000-7. View in: PubMed

  199. Matrix-bound growth factors in tissue repair. Swiss Med Wkly. 2007 Mar 02; 137 Suppl 155:72S-76S. View in: PubMed

  200. Exploiting lymphatic transport and complement activation in nanoparticle vaccines. Nat Biotechnol. 2007 Oct; 25(10):1159-64. View in: PubMed

  201. Part II: Fibroblasts preferentially migrate in the direction of principal strain. Biomech Model Mechanobiol. 2008 Jun; 7(3):215-25. View in: PubMed

  202. Mechanisms of 3-D migration and matrix remodeling of fibroblasts within artificial ECMs. Acta Biomater. 2007 Sep; 3(5):615-29. View in: PubMed

  203. Enzymatic formation of modular cell-instructive fibrin analogs for tissue engineering. Biomaterials. 2007 Sep; 28(26):3856-66. View in: PubMed

  204. RNA interference targeting hypoxia inducible factor 1alpha reduces post-operative adhesions in rats. J Surg Res. 2007 Aug; 141(2):162-70. View in: PubMed

  205. PEG-SS-PPS: reduction-sensitive disulfide block copolymer vesicles for intracellular drug delivery. Biomacromolecules. 2007 Jun; 8(6):1966-72. View in: PubMed

  206. Part I: A novel in-vitro system for simultaneous mechanical stimulation and time-lapse microscopy in 3D. Biomech Model Mechanobiol. 2008 Jun; 7(3):203-14. View in: PubMed

  207. Enhanced intimal thickening of expanded polytetrafluoroethylene grafts coated with fibrin or fibrin-releasing vascular endothelial growth factor in the pig carotid artery interposition model. J Thorac Cardiovasc Surg. 2007 May; 133(5):1163-70. View in: PubMed

  208. Synthesis and in vitro characterization of an ABC triblock copolymer for siRNA delivery. Bioconjug Chem. 2007 May-Jun; 18(3):736-45. View in: PubMed

  209. Analysis of progenitor cell-scaffold combinations by in vivo non-invasive photonic imaging. Biomaterials. 2007 Jun; 28(17):2718-28. View in: PubMed

  210. High-throughput cell manipulation using ultrasound fields. Conf Proc IEEE Eng Med Biol Soc. 2004; 2004:2571-4. View in: PubMed

  211. Recombinant protein-co-PEG networks as cell-adhesive and proteolytically degradable hydrogel matrixes. Part II: biofunctional characteristics. Biomacromolecules. 2006 Nov; 7(11):3019-29. View in: PubMed

  212. Targeting dendritic cells with biomaterials: developing the next generation of vaccines. Trends Immunol. 2006 Dec; 27(12):573-9. View in: PubMed

  213. Polymer stent coating for prevention of neointimal hyperplasia. J Invasive Cardiol. 2006 Sep; 18(9):423-6; discussion 427. View in: PubMed

  214. Doxorubicin encapsulation and diffusional release from stable, polymeric, hydrogel nanoparticles. Eur J Pharm Sci. 2006 Oct 01; 29(2):120-9. View in: PubMed

  215. Discovery of a sulfated tetrapeptide that binds to vascular endothelial growth factor. Acta Biomater. 2005 Jul; 1(4):451-9. View in: PubMed

  216. Poly (4-vinylimidazole) as nonviral gene carrier: in vitro and in vivo transfection. Acta Biomater. 2005 Mar; 1(2):165-72. View in: PubMed

  217. Non-viral gene delivery: multifunctional polyplexes as locally triggerable nonviral vectors. Gene Ther. 2006 Oct; 13(19):1371-2. View in: PubMed

  218. In vivo targeting of dendritic cells in lymph nodes with poly(propylene sulfide) nanoparticles. J Control Release. 2006 May 01; 112(1):26-34. View in: PubMed

  219. Activation of cell-survival transcription factor NFkappaB in L1Ig6-stimulated endothelial cells. J Biomed Mater Res A. 2006 Jun 01; 77(3):542-50. View in: PubMed

  220. Peptide-matrix-mediated gene transfer of an oxygen-insensitive hypoxia-inducible factor-1alpha variant for local induction of angiogenesis. Proc Natl Acad Sci U S A. 2006 Feb 21; 103(8):2506-11. View in: PubMed

  221. Pattern stability under cell culture conditions--a comparative study of patterning methods based on PLL-g-PEG background passivation. Biomaterials. 2006 Apr; 27(12):2534-41. View in: PubMed

  222. PPS-PEG surface coating to reduce thrombogenicity of small diameter ePTFE vascular grafts. Int J Artif Organs. 2005 Oct; 28(10):993-1002. View in: PubMed

  223. Interfacial reactivity of block copolymers: understanding the amphiphile-to-hydrophile transition. Langmuir. 2005 Sep 27; 21(20):9149-53. View in: PubMed

  224. 3D morphology of cell cultures: a quantitative approach using micrometer synchrotron light tomography. Microsc Res Tech. 2005 Apr 15; 66(6):289-98. View in: PubMed

  225. Enhanced endothelial cell retention on shear-stressed synthetic vascular grafts precoated with RGD-cross-linked fibrin. Tissue Eng. 2005 May-Jun; 11(5-6):887-95. View in: PubMed

  226. Molecularly engineered PEG hydrogels: a novel model system for proteolytically mediated cell migration. Biophys J. 2005 Aug; 89(2):1374-88. View in: PubMed

  227. Recombinant protein-co-PEG networks as cell-adhesive and proteolytically degradable hydrogel matrixes. Part I: Development and physicochemical characteristics. Biomacromolecules. 2005 May-Jun; 6(3):1226-38. View in: PubMed

  228. Glucose-oxidase based self-destructing polymeric vesicles. Langmuir. 2004 Apr 27; 20(9):3487-91. View in: PubMed

  229. Sustained release of human growth hormone from in situ forming hydrogels using self-assembly of fluoroalkyl-ended poly(ethylene glycol). Biomaterials. 2005 Sep; 26(25):5259-66. View in: PubMed

  230. Effects of protein and gene transfer of the angiopoietin-1 fibrinogen-like receptor-binding domain on endothelial and vessel organization. J Biol Chem. 2005 Jun 10; 280(23):22445-53. View in: PubMed

  231. Amphiphilic hydrogel nanoparticles. Preparation, characterization, and preliminary assessment as new colloidal drug carriers. Langmuir. 2005 Mar 15; 21(6):2605-13. View in: PubMed

  232. Enhancement of bone healing using non-glycosylated rhBMP-2 released from a fibrin matrix in dogs and cats. J Small Anim Pract. 2005 Jan; 46(1):17-21. View in: PubMed

  233. Poly(ethylene glycol) hydrogels formed by conjugate addition with controllable swelling, degradation, and release of pharmaceutically active proteins. J Control Release. 2005 Feb 16; 102(3):619-27. View in: PubMed

  234. Non-viral gene delivery for local and controlled DNA release. J Control Release. 2005 Jan 20; 102(1):263-75. View in: PubMed

  235. Network formation and degradation behavior of hydrogels formed by Michael-type addition reactions. Biomacromolecules. 2005 Jan-Feb; 6(1):290-301. View in: PubMed

  236. Synthetic biomaterials as instructive extracellular microenvironments for morphogenesis in tissue engineering. Nat Biotechnol. 2005 Jan; 23(1):47-55. View in: PubMed

  237. Oxidation-sensitive polymeric nanoparticles. Langmuir. 2005 Jan 04; 21(1):411-7. View in: PubMed

  238. Bone repair with a form of BMP-2 engineered for incorporation into fibrin cell ingrowth matrices. Biotechnol Bioeng. 2005 Feb 05; 89(3):253-62. View in: PubMed

  239. Neurite extension and in vitro myelination within three-dimensional modified fibrin matrices. J Neurobiol. 2005 Apr; 63(1):1-14. View in: PubMed

  240. Heterophilic interactions between cell adhesion molecule L1 and alphavbeta3-integrin induce HUVEC process extension in vitro and angiogenesis in vivo. Angiogenesis. 2004; 7(3):213-23. View in: PubMed

  241. Endothelial cell proliferation and progenitor maturation by fibrin-bound VEGF variants with differential susceptibilities to local cellular activity. J Control Release. 2005 Jan 03; 101(1-3):93-109. View in: PubMed

  242. Towards a fully synthetic substitute of alginate: optimization of a thermal gelation/chemical cross-linking scheme ("tandem" gelation) for the production of beads and liquid-core capsules. Biotechnol Bioeng. 2004 Dec 20; 88(6):740-9. View in: PubMed

  243. Matrix-bound sixth Ig-like domain of cell adhesion molecule L1 acts as an angiogenic factor by ligating alphavbeta3-integrin and activating VEGF-R2. Microvasc Res. 2004 Nov; 68(3):169-78. View in: PubMed

  244. Mechanical properties, proteolytic degradability and biological modifications affect angiogenic process extension into native and modified fibrin matrices in vitro. Biomaterials. 2005 Apr; 26(12):1369-79. View in: PubMed

  245. Tissue and cell engineering. Curr Opin Biotechnol. 2004 Oct; 15(5):381-2. View in: PubMed

  246. A hydrogel system for stimulus-responsive, oxygen-sensitive in situ gelation. J Biomater Sci Polym Ed. 2004; 15(7):895-904. View in: PubMed

  247. Biomaterials science and high-throughput screening. Nat Biotechnol. 2004 Jul; 22(7):828-9. View in: PubMed

  248. The selective modulation of endothelial cell mobility on RGD peptide containing surfaces by YIGSR peptides. Biomaterials. 2005 Jan; 26(2):167-74. View in: PubMed

  249. Bovine primary chondrocyte culture in synthetic matrix metalloproteinase-sensitive poly(ethylene glycol)-based hydrogels as a scaffold for cartilage repair. Tissue Eng. 2004 Mar-Apr; 10(3-4):515-22. View in: PubMed

  250. Towards a fully-synthetic substitute of alginate: development of a new process using thermal gelation and chemical cross-linking. Biomaterials. 2004 Sep; 25(21):5115-24. View in: PubMed

  251. Cell-demanded liberation of VEGF121 from fibrin implants induces local and controlled blood vessel growth. Circ Res. 2004 Apr 30; 94(8):1124-32. View in: PubMed

  252. Treatment of nonunions with nonglycosylated recombinant human bone morphogenetic protein-2 delivered from a fibrin matrix. Vet Surg. 2004 Mar-Apr; 33(2):112-8. View in: PubMed

  253. Bone healing in the rat and dog with nonglycosylated BMP-2 demonstrating low solubility in fibrin matrices. J Orthop Res. 2004 Mar; 22(2):376-81. View in: PubMed

  254. Synthetic extracellular matrices for in situ tissue engineering. Biotechnol Bioeng. 2004 Apr 05; 86(1):27-36. View in: PubMed

  255. Oxidation-responsive polymeric vesicles. Nat Mater. 2004 Mar; 3(3):183-9. View in: PubMed

  256. MMP-2 sensitive, VEGF-bearing bioactive hydrogels for promotion of vascular healing. J Biomed Mater Res A. 2004 Mar 15; 68(4):704-16. View in: PubMed

  257. The effect of the linker on the hydrolysis rate of drug-linked ester bonds. J Control Release. 2004 Mar 05; 95(2):291-300. View in: PubMed

  258. Engineered fibrin matrices for functional display of cell membrane-bound growth factor-like activities: study of angiogenic signaling by ephrin-B2. Biomaterials. 2004 Jul; 25(16):3245-57. View in: PubMed

  259. Diffusion NMR spectroscopy for the characterization of the size and interactions of colloidal matter: the case of vesicles and nanoparticles. J Am Chem Soc. 2004 Feb 25; 126(7):2142-7. View in: PubMed

  260. RGD-containing peptide GCRGYGRGDSPG reduces enhancement of osteoblast differentiation by poly(L-lysine)-graft-poly(ethylene glycol)-coated titanium surfaces. J Biomed Mater Res A. 2004 Mar 01; 68(3):458-72. View in: PubMed

  261. N-terminal alpha-dystroglycan binds to different extracellular matrix molecules expressed in regenerating peripheral nerves in a protein-mediated manner and promotes neurite extension of PC12 cells. Mol Cell Neurosci. 2003 Dec; 24(4):1062-73. View in: PubMed

  262. Biopolymeric delivery matrices for angiogenic growth factors. Cardiovasc Pathol. 2003 Nov-Dec; 12(6):295-310. View in: PubMed

  263. Materials as morphogenetic guides in tissue engineering. Curr Opin Biotechnol. 2003 Oct; 14(5):551-8. View in: PubMed

  264. Tissue and cell engineering. Curr Opin Biotechnol. 2003 Oct; 14(5):517-9. View in: PubMed

  265. Cell-demanded release of VEGF from synthetic, biointeractive cell ingrowth matrices for vascularized tissue growth. FASEB J. 2003 Dec; 17(15):2260-2. View in: PubMed

  266. Peptide functionalized poly(L-lysine)-g-poly(ethylene glycol) on titanium: resistance to protein adsorption in full heparinized human blood plasma. Biomaterials. 2003 Dec; 24(27):4949-58. View in: PubMed

  267. Michael-type addition as a tool for surface functionalization. Bioconjug Chem. 2003 Sep-Oct; 14(5):967-73. View in: PubMed

  268. Evaluation of pH-dependent membrane-disruptive properties of poly(acrylic acid) derived polymers. Eur J Pharm Biopharm. 2003 Sep; 56(2):237-46. View in: PubMed

  269. Synthesis and physicochemical characterization of end-linked poly(ethylene glycol)-co-peptide hydrogels formed by Michael-type addition. Biomacromolecules. 2003 May-Jun; 4(3):713-22. View in: PubMed

  270. Materials science. Enhancing drug function. Science. 2003 Apr 25; 300(5619):595-6. View in: PubMed

  271. Repair of bone defects using synthetic mimetics of collagenous extracellular matrices. Nat Biotechnol. 2003 May; 21(5):513-8. View in: PubMed

  272. RGD-grafted poly-L-lysine-graft-(polyethylene glycol) copolymers block non-specific protein adsorption while promoting cell adhesion. Biotechnol Bioeng. 2003 Jun 30; 82(7):784-90. View in: PubMed

  273. Chemisorbed poly(propylene sulphide)-based copolymers resist biomolecular interactions. Nat Mater. 2003 Apr; 2(4):259-64. View in: PubMed

  274. Synthetic matrix metalloproteinase-sensitive hydrogels for the conduction of tissue regeneration: engineering cell-invasion characteristics. Proc Natl Acad Sci U S A. 2003 Apr 29; 100(9):5413-8. View in: PubMed

  275. Electrochemical optical waveguide lightmode spectroscopy (EC-OWLS): a pilot study using evanescent-field optical sensing under voltage control to monitor polycationic polymer adsorption onto indium tin oxide (ITO)-coated waveguide chips. Biotechnol Bioeng. 2003 May 20; 82(4):465-73. View in: PubMed

  276. Water-borne, in situ crosslinked biomaterials from phase-segregated precursors. J Biomed Mater Res A. 2003 Mar 01; 64(3):447-56. View in: PubMed

  277. Photopolymerized hyaluronic acid-based hydrogels and interpenetrating networks. Biomaterials. 2003 Mar; 24(6):893-900. View in: PubMed

  278. Biologically engineered protein-graft-poly(ethylene glycol) hydrogels: a cell adhesive and plasmin-degradable biosynthetic material for tissue repair. Biomacromolecules. 2002 Jul-Aug; 3(4):710-23. View in: PubMed

  279. Poly(ethylene glycol) block copolymers. J Biotechnol. 2002 Mar; 90(1):3-15. View in: PubMed

  280. Sterically blocking adhesion of cells to biological surfaces with a surface-active copolymer containing poly(ethylene glycol) and phenylboronic acid. J Biomed Mater Res. 2002 Mar 15; 59(4):618-31. View in: PubMed

  281. Conjugate addition reactions combined with free-radical cross-linking for the design of materials for tissue engineering. Biomacromolecules. 2001; 2(2):430-41. View in: PubMed

  282. Systematic modulation of Michael-type reactivity of thiols through the use of charged amino acids. Bioconjug Chem. 2001 Nov-Dec; 12(6):1051-6. View in: PubMed

  283. Blocking adhesion to cell and tissue surfaces by the chemisorption of a poly-L-lysine-graft-(poly(ethylene glycol); phenylboronic acid) copolymer. Biomacromolecules. 2000; 1(4):523-33. View in: PubMed

  284. Molecular properties of fibrin-based matrices for promotion of angiogenesis in vitro. Microvasc Res. 2001 Nov; 62(3):315-26. View in: PubMed

  285. Protein delivery from materials formed by self-selective conjugate addition reactions. J Control Release. 2001 Sep 11; 76(1-2):11-25. View in: PubMed

  286. Fibronectin modulates macrophage adhesion and FBGC formation: the role of RGD, PHSRN, and PRRARV domains. J Biomed Mater Res. 2001 Apr; 55(1):79-88. View in: PubMed

  287. Covalently conjugated VEGF--fibrin matrices for endothelialization. J Control Release. 2001 May 14; 72(1-3):101-13. View in: PubMed

  288. Development of growth factor fusion proteins for cell-triggered drug delivery. FASEB J. 2001 May; 15(7):1300-2. View in: PubMed

  289. Controlled release of nerve growth factor from a heparin-containing fibrin-based cell ingrowth matrix. J Control Release. 2000 Oct 03; 69(1):149-58. View in: PubMed

  290. Fibrin gel as a three dimensional matrix in cardiovascular tissue engineering. Eur J Cardiothorac Surg. 2000 May; 17(5):587-91. View in: PubMed

  291. Enzymatic incorporation of bioactive peptides into fibrin matrices enhances neurite extension. Nat Biotechnol. 2000 Apr; 18(4):415-9. View in: PubMed

  292. Three-dimensional migration of neurites is mediated by adhesion site density and affinity. J Biol Chem. 2000 Mar 10; 275(10):6813-8. View in: PubMed

  293. Development of fibrin derivatives for controlled release of heparin-binding growth factors. J Control Release. 2000 Apr 03; 65(3):389-402. View in: PubMed

  294. Intraarterial protein delivery via intimally-adherent bilayer hydrogels. J Control Release. 2000 Feb 14; 64(1-3):205-15. View in: PubMed

  295. Pharmacokinetics, pharmacodynamics, and analgesic effects of morphine after rectal, intramuscular, and intravenous administration in dogs. Am J Vet Res. 2000 Jan; 61(1):24-8. View in: PubMed

  296. Incorporation of heparin-binding peptides into fibrin gels enhances neurite extension: an example of designer matrices in tissue engineering. FASEB J. 1999 Dec; 13(15):2214-24. View in: PubMed

  297. In vitro and in vivo performance of porcine islets encapsulated in interfacially photopolymerized poly(ethylene glycol) diacrylate membranes. Cell Transplant. 1999 May-Jun; 8(3):293-306. View in: PubMed

  298. Bioactive biomaterials. Curr Opin Biotechnol. 1999 Apr; 10(2):123-9. View in: PubMed

  299. Murine macrophage behavior on peptide-grafted polyethyleneglycol-containing networks. Biotechnol Bioeng. 1998 Jul 05; 59(1):2-9. View in: PubMed

  300. A sensitivity study of the key parameters in the interfacial photopolymerization of poly(ethylene glycol) diacrylate upon porcine islets. Biotechnol Bioeng. 1998 Mar 20; 57(6):655-65. View in: PubMed

  301. Biotechnology. A new-for-old urinary bladder. Nature. 1999 Mar 18; 398(6724):198-9. View in: PubMed

  302. Rapid induction of functional and morphological continuity between severed ends of mammalian or earthworm myelinated axons. J Neurosci. 1999 Apr 01; 19(7):2442-54. View in: PubMed

  303. Cross-linking exogenous bifunctional peptides into fibrin gels with factor XIIIa. Bioconjug Chem. 1999 Jan-Feb; 10(1):75-81. View in: PubMed

  304. Reduction of fibrous adhesion formation by a copolymer possessing an affinity for anionic surfaces. J Biomed Mater Res. 1998 Oct; 42(1):55-65. View in: PubMed

  305. Characterization of permeability and network structure of interfacially photopolymerized poly(ethylene glycol) diacrylate hydrogels. Biomaterials. 1998 Jul; 19(14):1287-94. View in: PubMed

  306. Surface characteristics and biocompatibility of lactide-based poly(ethylene glycol) scaffolds for tissue engineering. J Biomater Sci Polym Ed. 1998; 9(7):667-80. View in: PubMed

  307. Chemical modification and photograft polymerization upon expanded poly(tetrafluoroethylene). J Biomater Sci Polym Ed. 1998; 9(5):407-26. View in: PubMed

  308. Biomaterials in tissue engineering. Biotechnology (N Y). 1995 Jun; 13(6):565-76. View in: PubMed

  309. Immunoisolation of adult porcine islets for the treatment of diabetes mellitus. The use of photopolymerizable polyethylene glycol in the conformal coating of mass-isolated porcine islets. Ann N Y Acad Sci. 1997 Dec 31; 831:332-43. View in: PubMed

  310. Effects of fibrin micromorphology on neurite growth from dorsal root ganglia cultured in three-dimensional fibrin gels. J Biomed Mater Res. 1998 Jun 15; 40(4):551-9. View in: PubMed

  311. Self-assembly and steric stabilization at heterogeneous, biological surfaces using adsorbing block copolymers. Chem Biol. 1998 Mar; 5(3):177-83. View in: PubMed

  312. Incorporation of adhesion peptides into nonadhesive hydrogels useful for tissue resurfacing. J Biomed Mater Res. 1998 Feb; 39(2):266-76. View in: PubMed

  313. Alkylated cellulosic membranes with enhanced albumin affinity: influence of competing proteins. J Biomater Sci Polym Ed. 1995; 7(7):563-75. View in: PubMed

  314. Separation of the arterial wall from blood contact using hydrogel barriers reduces intimal thickening after balloon injury in the rat: the roles of medial and luminal factors in arterial healing. Proc Natl Acad Sci U S A. 1996 Nov 12; 93(23):13188-93. View in: PubMed

  315. Effects of fibinolysis on neurite growth from dorsal root ganglia cultured in two- and three-dimensional fibrin gels. J Comp Neurol. 1996 Feb 12; 365(3):380-91. View in: PubMed

  316. Efficacy of adhesion barriers. Resorbable hydrogel, oxidized regenerated cellulose and hyaluronic acid. J Reprod Med. 1996 Mar; 41(3):149-54. View in: PubMed

  317. Adhesion prevention with ancrod released via a tissue-adherent hydrogel. J Surg Res. 1996 Feb 15; 61(1):58-64. View in: PubMed

  318. Alkylation of cellulosic membranes results in reduced complement activation. J Biomater Sci Polym Ed. 1996; 7(8):707-14. View in: PubMed

  319. Comparison of covalently and physically cross-linked polyethylene glycol-based hydrogels for the prevention of postoperative adhesions in a rat model. Biomaterials. 1995 Oct; 16(15):1153-6. View in: PubMed

  320. Local release of fibrinolytic agents for adhesion prevention. J Surg Res. 1995 Dec; 59(6):759-63. View in: PubMed

  321. Covalently immobilized laminin peptide Tyr-Ile-Gly-Ser-Arg (YIGSR) supports cell spreading and co-localization of the 67-kilodalton laminin receptor with alpha-actinin and vinculin. J Biol Chem. 1993 Apr 15; 268(11):8053-9. View in: PubMed

  322. Interfacial photopolymerization of poly(ethylene glycol)-based hydrogels upon alginate-poly(l-lysine) microcapsules for enhanced biocompatibility. Biomaterials. 1993 Oct; 14(13):1008-16. View in: PubMed

  323. Prevention of postoperative adhesions in the rat by in situ photopolymerization of bioresorbable hydrogel barriers. Obstet Gynecol. 1994 Jan; 83(1):59-64. View in: PubMed

  324. Optimization of photopolymerized bioerodible hydrogel properties for adhesion prevention. J Biomed Mater Res. 1994 Jul; 28(7):831-8. View in: PubMed

  325. Efficacy of a resorbable hydrogel barrier, oxidized regenerated cellulose, and hyaluronic acid in the prevention of ovarian adhesions in a rabbit model. Fertil Steril. 1994 Sep; 62(3):630-4. View in: PubMed

  326. Inhibition of thrombosis and intimal thickening by in situ photopolymerization of thin hydrogel barriers. Proc Natl Acad Sci U S A. 1994 Jun 21; 91(13):5967-71. View in: PubMed

  327. Design, characterization, and one-point in vivo calibration of a subcutaneously implanted glucose electrode. Anal Chem. 1994 Oct 01; 66(19):3131-8. View in: PubMed

  328. Polymer networks with grafted cell adhesion peptides for highly biospecific cell adhesive substrates. Anal Biochem. 1994 Nov 01; 222(2):380-8. View in: PubMed

  329. Polyimide-polyethylene glycol block copolymers: synthesis, characterization, and initial evaluation as a biomaterial. J Biomater Sci Polym Ed. 1994; 6(4):313-23. View in: PubMed

  330. Molecular weight dependence of calcification of polyethylene glycol hydrogels. Biomaterials. 1994 Sep; 15(11):921-5. View in: PubMed

  331. Densely crosslinked polymer networks of poly(ethylene glycol) in trimethylolpropane triacrylate for cell-adhesion-resistant surfaces. J Biomed Mater Res. 1995 Feb; 29(2):207-15. View in: PubMed

  332. A new photopolymerizable blood vessel glue that seals human vessel anastomoses without augmenting thrombogenicity. Plast Reconstr Surg. 1995 Apr; 95(5):901-7. View in: PubMed

  333. Photo-crosslinked copolymers of 2-hydroxyethyl methacrylate, poly(ethylene glycol) tetra-acrylate and ethylene dimethacrylate for improving biocompatibility of biosensors. Biomaterials. 1995 Mar; 16(5):389-96. View in: PubMed

  334. Visualization and analysis of mural thrombogenesis on collagen, polyurethane and nylon. Biomaterials. 1986 Sep; 7(5):354-63. View in: PubMed

  335. The short-term blood biocompatibility of poly(hydroxyethyl methacrylate-co-methyl methacrylate) in an in vitro flow system measured by digital videomicroscopy. J Biomater Sci Polym Ed. 1989; 1(2):123-46. View in: PubMed

  336. Covalent surface immobilization of Arg-Gly-Asp- and Tyr-Ile-Gly-Ser-Arg-containing peptides to obtain well-defined cell-adhesive substrates. Anal Biochem. 1990 Jun; 187(2):292-301. View in: PubMed

  337. Rapidly degraded terpolymers of dl-lactide, glycolide, and epsilon-caprolactone with increased hydrophilicity by copolymerization with polyethers. J Biomed Mater Res. 1990 Oct; 24(10):1397-411. View in: PubMed

  338. Covalently attached GRGD on polymer surfaces promotes biospecific adhesion of mammalian cells. Ann N Y Acad Sci. 1990; 589:261-70. View in: PubMed

  339. Local thrombin synthesis and fibrin formation in an in vitro thrombosis model result in platelet recruitment and thrombus stabilization on collagen in heparinized blood. J Lab Clin Med. 1990 Nov; 116(5):636-50. View in: PubMed

  340. Biological responses to polyethylene oxide modified polyethylene terephthalate surfaces. J Biomed Mater Res. 1991 Jul; 25(7):829-43. View in: PubMed

  341. Solution technique to incorporate polyethylene oxide and other water-soluble polymers into surfaces of polymeric biomaterials. Biomaterials. 1991 Mar; 12(2):144-53. View in: PubMed

  342. Human endothelial cell interactions with surface-coupled adhesion peptides on a nonadhesive glass substrate and two polymeric biomaterials. J Biomed Mater Res. 1991 Feb; 25(2):223-42. View in: PubMed

  343. An RGD spacing of 440 nm is sufficient for integrin alpha V beta 3-mediated fibroblast spreading and 140 nm for focal contact and stress fiber formation. J Cell Biol. 1991 Sep; 114(5):1089-100. View in: PubMed

  344. Vascular endothelial cell adhesion and spreading promoted by the peptide REDV of the IIICS region of plasma fibronectin is mediated by integrin alpha 4 beta 1. J Biol Chem. 1992 Jul 15; 267(20):14019-26. View in: PubMed

  345. Immobilized amines and basic amino acids as mimetic heparin-binding domains for cell surface proteoglycan-mediated adhesion. J Biol Chem. 1992 May 15; 267(14):10133-41. View in: PubMed

  346. Poly(ethylene oxide)-graft-poly(L-lysine) copolymers to enhance the biocompatibility of poly(L-lysine)-alginate microcapsule membranes. Biomaterials. 1992; 13(12):863-70. View in: PubMed

  347. Avoidance of photoactivation in the epifluorescence video microscopic observation of thrombosis. J Biomed Mater Res. 1992 Nov; 26(11):1535-42. View in: PubMed

  348. Surface-grafted cell-binding peptides in tissue engineering of the vascular graft. Ann N Y Acad Sci. 1992 Oct 13; 665:253-8. View in: PubMed

  349. Tissue response to intraperitoneal implants of polyethylene oxide-modified polyethylene terephthalate. Biomaterials. 1992; 13(8):505-10. View in: PubMed

  350. Surface-immobilized polyethylene oxide for bacterial repellence. Biomaterials. 1992; 13(7):417-20. View in: PubMed

  351. Endothelial cell-selective materials for tissue engineering in the vascular graft via a new receptor. Biotechnology (N Y). 1991 Jun; 9(6):568-72. View in: PubMed

  352. Tissue engineering in the vascular graft. Cytotechnology. 1992; 10(3):189-204. View in: PubMed
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