Jeffrey Hubbell

Barry L. Maclean Professor
Biosciences Graduate Program Association
  1. Treatment of peanut allergy and colitis in mice via the intestinal release of butyrate from polymeric micelles. Nat Biomed Eng. 2023 Jan; 7(1):38-55. View in: PubMed

  2. Tumor Cell-Surface Binding of Immune Stimulating Polymeric Glyco-Adjuvant via Cysteine-Reactive Pyridyl Disulfide Promotes Antitumor Immunity. ACS Cent Sci. 2022 Oct 26; 8(10):1435-1446. View in: PubMed

  3. Severe COVID-19 induces autoantibodies against angiotensin II that correlate with blood pressure dysregulation and disease severity. Sci Adv. 2022 10 07; 8(40):eabn3777. View in: PubMed

  4. Therapeutic arteriogenesis by factor-decorated fibrin matrices promotes wound healing in diabetic mice. J Tissue Eng. 2022 Jan-Dec; 13:20417314221119615. View in: PubMed

  5. Immunostimulatory Polymers as Adjuvants, Immunotherapies, and Delivery Systems. Macromolecules. 2022 Aug 23; 55(16):6913-6937. View in: PubMed

  6. Robust coupling of angiogenesis and osteogenesis by VEGF-decorated matrices for bone regeneration. Acta Biomater. 2022 09 01; 149:111-125. View in: PubMed

  7. Therapeutic use of a2-antiplasmin as an antifibrinolytic and hemostatic agent in surgery and regenerative medicine. NPJ Regen Med. 2022 Jun 30; 7(1):34. View in: PubMed

  8. Masking the immunotoxicity of interleukin-12 by fusing it with a domain of its receptor via a tumour-protease-cleavable linker. Nat Biomed Eng. 2022 07; 6(7):819-829. View in: PubMed

  9. Kidney repair and regeneration: perspectives of the NIDDK (Re)Building a Kidney consortium. Kidney Int. 2022 05; 101(5):845-853. View in: PubMed

  10. VEGF-A, PDGF-BB and HB-EGF engineered for promiscuous super affinity to the extracellular matrix improve wound healing in a model of type 1 diabetes. NPJ Regen Med. 2021 Nov 18; 6(1):76. View in: PubMed

  11. SARS-CoV-2 infection induces cross-reactive autoantibodies against angiotensin II. medRxiv. 2021 Nov 02. View in: PubMed

  12. Overcoming transport barriers to immunotherapy. Drug Deliv Transl Res. 2021 12; 11(6):2273-2275. View in: PubMed

  13. Generation of potent cellular and humoral immunity against SARS-CoV-2 antigens via conjugation to a polymeric glyco-adjuvant. Biomaterials. 2021 11; 278:121159. View in: PubMed

  14. Lymph Node-Targeted Synthetically Glycosylated Antigen Leads to Antigen-Specific Immunological Tolerance. Front Immunol. 2021; 12:714842. View in: PubMed

  15. Polymersomes Decorated with the SARS-CoV-2 Spike Protein Receptor-Binding Domain Elicit Robust Humoral and Cellular Immunity. ACS Cent Sci. 2021 Aug 25; 7(8):1368-1380. View in: PubMed

  16. Robust Angiogenesis and Arteriogenesis in the Skin of Diabetic Mice by Transient Delivery of Engineered VEGF and PDGF-BB Proteins in Fibrin Hydrogels. Front Bioeng Biotechnol. 2021; 9:688467. View in: PubMed

  17. Immunoengineering approaches for cytokine therapy. Am J Physiol Cell Physiol. 2021 08 01; 321(2):C369-C383. View in: PubMed

  18. Engineered bridge protein with dual affinity for bone morphogenetic protein-2 and collagen enhances bone regeneration for spinal fusion. Sci Adv. 2021 06; 7(24). View in: PubMed

  19. Polymersomes decorated with SARS-CoV-2 spike protein receptor binding domain elicit robust humoral and cellular immunity. bioRxiv. 2021 Apr 08. View in: PubMed

  20. Lymphangiogenesis-inducing vaccines elicit potent and long-lasting T cell immunity against melanomas. Sci Adv. 2021 03; 7(13). View in: PubMed

  21. Soluble N-Acetylgalactosamine-Modified Antigens Enhance Hepatocyte-Dependent Antigen Cross-Presentation and Result in Antigen-Specific CD8+ T Cell Tolerance Development. Front Immunol. 2021; 12:555095. View in: PubMed

  22. Persistent antigen exposure via the eryptotic pathway drives terminal T cell dysfunction. Sci Immunol. 2021 02 26; 6(56). View in: PubMed

  23. A Cationic Micelle Complex Improves CD8+ T Cell Responses in Vaccination Against Unmodified Protein Antigen. ACS Biomater Sci Eng. 2016 Feb 08; 2(2):231-240. View in: PubMed

  24. Suppression of Rheumatoid Arthritis by Enhanced Lymph Node Trafficking of Engineered Interleukin-10 in Murine Models. Arthritis Rheumatol. 2021 05; 73(5):769-778. View in: PubMed

  25. Publisher Correction: Prolonged residence of an albumin-IL-4 fusion protein in secondary lymphoid organs ameliorates experimental autoimmune encephalomyelitis. Nat Biomed Eng. 2020 Nov; 4(11):1117. View in: PubMed

  26. Prolonged residence of an albumin-IL-4 fusion protein in secondary lymphoid organs ameliorates experimental autoimmune encephalomyelitis. Nat Biomed Eng. 2021 05; 5(5):387-398. View in: PubMed

  27. Thermally-induced glass formation from hydrogel nanoparticles. Soft Matter. 2006 Nov 15; 2(12):1067-1075. View in: PubMed

  28. An optimized antigen-protein fusion. Nat Biomed Eng. 2020 06; 4(6):583-584. View in: PubMed

  29. Collagen-binding IL-12 enhances tumour inflammation and drives the complete remission of established immunologically cold mouse tumours. Nat Biomed Eng. 2020 05; 4(5):531-543. View in: PubMed

  30. Engineering Targeting Materials for Therapeutic Cancer Vaccines. Front Bioeng Biotechnol. 2020; 8:19. View in: PubMed

  31. Conferring extracellular matrix affinity enhances local therapeutic efficacy of anti-TNF-a antibody in a murine model of rheumatoid arthritis. Arthritis Res Ther. 2019 12 23; 21(1):298. View in: PubMed

  32. Recruitment of CD103+ dendritic cells via tumor-targeted chemokine delivery enhances efficacy of checkpoint inhibitor immunotherapy. Sci Adv. 2019 12; 5(12):eaay1357. View in: PubMed

  33. Targeting inflammatory sites through collagen affinity enhances the therapeutic efficacy of anti-inflammatory antibodies. Sci Adv. 2019 11; 5(11):eaay1971. View in: PubMed

  34. Growth factors with enhanced syndecan binding generate tonic signalling and promote tissue healing. Nat Biomed Eng. 2020 04; 4(4):463-475. View in: PubMed

  35. Synthetic 3D PEG-Anisogel Tailored with Fibronectin Fragments Induce Aligned Nerve Extension. Biomacromolecules. 2019 11 11; 20(11):4075-4087. View in: PubMed

  36. Engineered collagen-binding serum albumin as a drug conjugate carrier for cancer therapy. Sci Adv. 2019 08; 5(8):eaaw6081. View in: PubMed

  37. Synthetically glycosylated antigens induce antigen-specific tolerance and prevent the onset of diabetes. Nat Biomed Eng. 2019 10; 3(10):817-829. View in: PubMed

  38. The heparin binding domain of von Willebrand factor binds to growth factors and promotes angiogenesis in wound healing. Blood. 2019 06 13; 133(24):2559-2569. View in: PubMed

  39. Targeted antibody and cytokine cancer immunotherapies through collagen affinity. Sci Transl Med. 2019 04 10; 11(487). View in: PubMed

  40. A Bioinspired Scaffold with Anti-Inflammatory Magnesium Hydroxide and Decellularized Extracellular Matrix for Renal Tissue Regeneration. ACS Cent Sci. 2019 Mar 27; 5(3):458-467. View in: PubMed

  41. A bioactive injectable bulking material; a potential therapeutic approach for stress urinary incontinence. Biomaterials. 2019 06; 206:41-48. View in: PubMed

  42. Combination of Synthetic Long Peptides and XCL1 Fusion Proteins Results in Superior Tumor Control. Front Immunol. 2019; 10:294. View in: PubMed

  43. Quantitative intrinsic auto-cathodoluminescence can resolve spectral signatures of tissue-isolated collagen extracellular matrix. Commun Biol. 2019; 2:69. View in: PubMed

  44. Trojan horses for immunotherapy. Nat Nanotechnol. 2019 03; 14(3):196-197. View in: PubMed

  45. Antigens reversibly conjugated to a polymeric glyco-adjuvant induce protective humoral and cellular immunity. Nat Mater. 2019 02; 18(2):175-185. View in: PubMed

  46. Improving Efficacy and Safety of Agonistic Anti-CD40 Antibody Through Extracellular Matrix Affinity. Mol Cancer Ther. 2018 11; 17(11):2399-2411. View in: PubMed

  47. Fiber density of collagen grafts impacts rabbit urethral regeneration. Sci Rep. 2018 07 03; 8(1):10057. View in: PubMed

  48. Laminin heparin-binding peptides bind to several growth factors and enhance diabetic wound healing. Nat Commun. 2018 06 04; 9(1):2163. View in: PubMed

  49. Modified Magnesium Hydroxide Nanoparticles Inhibit the Inflammatory Response to Biodegradable Poly(lactide- co-glycolide) Implants. ACS Nano. 2018 07 24; 12(7):6917-6925. View in: PubMed

  50. Adaptive enhanced sampling by force-biasing using neural networks. J Chem Phys. 2018 Apr 07; 148(13):134108. View in: PubMed

  51. Microfluidic production of bioactive fibrin micro-beads embedded in crosslinked collagen used as an injectable bulking agent for urinary incontinence treatment. Acta Biomater. 2018 02; 67:156-166. View in: PubMed

  52. Matrix-binding checkpoint immunotherapies enhance antitumor efficacy and reduce adverse events. Sci Transl Med. 2017 Nov 08; 9(415). View in: PubMed

  53. Immunoisolation of murine islet allografts in vascularized sites through conformal coating with polyethylene glycol. Am J Transplant. 2018 03; 18(3):590-603. View in: PubMed

  54. Oxidation-sensitive polymersomes as vaccine nanocarriers enhance humoral responses against Lassa virus envelope glycoprotein. Virology. 2017 12; 512:161-171. View in: PubMed

  55. Bioengineering strategies for inducing tolerance in autoimmune diabetes. Adv Drug Deliv Rev. 2017 05 15; 114:256-265. View in: PubMed

  56. Corrigendum: Advances in pancreatic islet monolayer culture on glass surfaces enable super-resolution microscopy and insights into beta cell ciliogenesis and proliferation. Sci Rep. 2017 05 09; 7:46801. View in: PubMed

  57. Human Kunitz-type protease inhibitor engineered for enhanced matrix retention extends longevity of fibrin biomaterials. Biomaterials. 2017 Aug; 135:1-9. View in: PubMed

  58. Local induction of lymphangiogenesis with engineered fibrin-binding VEGF-C promotes wound healing by increasing immune cell trafficking and matrix remodeling. Biomaterials. 2017 07; 131:160-175. View in: PubMed

  59. Vaccine nanocarriers: Coupling intracellular pathways and cellular biodistribution to control CD4 vs CD8 T cell responses. Biomaterials. 2017 07; 132:48-58. View in: PubMed

  60. Advances in pancreatic islet monolayer culture on glass surfaces enable super-resolution microscopy and insights into beta cell ciliogenesis and proliferation. Sci Rep. 2017 04 12; 7:45961. View in: PubMed

  61. Toll-like receptor 8 agonist nanoparticles mimic immunomodulating effects of the live BCG vaccine and enhance neonatal innate and adaptive immune responses. J Allergy Clin Immunol. 2017 Nov; 140(5):1339-1350. View in: PubMed

  62. (Re)Building a Kidney. J Am Soc Nephrol. 2017 May; 28(5):1370-1378. View in: PubMed

  63. Primary Human and Rat ?-Cells Release the Intracellular Autoantigens GAD65, IA-2, and Proinsulin in Exosomes Together With Cytokine-Induced Enhancers of Immunity. Diabetes. 2017 02; 66(2):460-473. View in: PubMed

  64. Difference in suitable mechanical properties of three-dimensional, synthetic scaffolds for self-renewing mouse embryonic stem cells of different genetic backgrounds. J Biomed Mater Res B Appl Biomater. 2017 Nov; 105(8):2261-2268. View in: PubMed

  65. Engineered acellular collagen scaffold for endogenous cell guidance, a novel approach in urethral regeneration. Acta Biomater. 2016 10 01; 43:208-217. View in: PubMed

  66. IGF-1-containing multi-layered collagen-fibrin hybrid scaffolds for bladder tissue engineering. Acta Biomater. 2016 09 01; 41:75-85. View in: PubMed

  67. Aberrant Accumulation of the Diabetes Autoantigen GAD65 in Golgi Membranes in Conditions of ER Stress and Autoimmunity. Diabetes. 2016 09; 65(9):2686-99. View in: PubMed

  68. Fibronectin EDA and CpG synergize to enhance antigen-specific Th1 and cytotoxic responses. Vaccine. 2016 05 05; 34(21):2453-2459. View in: PubMed

  69. Hollow Mesoporous Plasmonic Nanoshells for Enhanced Solar Vapor Generation. Nano Lett. 2016 Apr 13; 16(4):2159-67. View in: PubMed

  70. TLR-3 stimulation improves anti-tumor immunity elicited by dendritic cell exosome-based vaccines in a murine model of melanoma. Sci Rep. 2015 Dec 03; 5:17622. View in: PubMed

  71. Engineered binding to erythrocytes induces immunological tolerance to E. coli asparaginase. Sci Adv. 2015 Jul; 1(6):e1500112. View in: PubMed

  72. Engineering growth factors for regenerative medicine applications. Acta Biomater. 2016 Jan; 30:1-12. View in: PubMed

  73. Memory of tolerance and induction of regulatory T cells by erythrocyte-targeted antigens. Sci Rep. 2015 Oct 29; 5:15907. View in: PubMed

  74. Kinetics of Ultrasonic Drug Delivery from Targeted Micelles. J Nanosci Nanotechnol. 2015 Mar; 15(3):2099-104. View in: PubMed

  75. Nanoparticle conjugation enhances the immunomodulatory effects of intranasally delivered CpG in house dust mite-allergic mice. Sci Rep. 2015 Sep 21; 5:14274. View in: PubMed

  76. Extracellular Matrix-Inspired Growth Factor Delivery Systems for Skin Wound Healing. Adv Wound Care (New Rochelle). 2015 Aug 01; 4(8):479-489. View in: PubMed

  77. Engineering antigen-specific immunological tolerance. Curr Opin Immunol. 2015 Aug; 35:80-8. View in: PubMed

  78. Crystalline Oligo(ethylene sulfide) Domains Define Highly Stable Supramolecular Block Copolymer Assemblies. ACS Nano. 2015 Jul 28; 9(7):6872-81. View in: PubMed

  79. Tubular Compressed Collagen Scaffolds for Ureteral Tissue Engineering in a Flow Bioreactor System. Tissue Eng Part A. 2015 Sep; 21(17-18):2334-45. View in: PubMed

  80. Prescription for a pharmacyte. Sci Transl Med. 2015 Jun 10; 7(291):291fs23. View in: PubMed

  81. 6-Thioguanine-loaded polymeric micelles deplete myeloid-derived suppressor cells and enhance the efficacy of T cell immunotherapy in tumor-bearing mice. Cancer Immunol Immunother. 2015 Aug; 64(8):1033-46. View in: PubMed

  82. Extracellular matrix-inspired growth factor delivery systems for bone regeneration. Adv Drug Deliv Rev. 2015 Nov 01; 94:41-52. View in: PubMed

  83. Extracellular matrix and growth factor engineering for controlled angiogenesis in regenerative medicine. Front Bioeng Biotechnol. 2015; 3:45. View in: PubMed

  84. Fibrin gels engineered with pro-angiogenic growth factors promote engraftment of pancreatic islets in extrahepatic sites in mice. Biotechnol Bioeng. 2015 Sep; 112(9):1916-26. View in: PubMed

  85. The TLR4 agonist fibronectin extra domain A is cryptic, exposed by elastase-2; use in a fibrin matrix cancer vaccine. Sci Rep. 2015 Feb 24; 5:8569. View in: PubMed

  86. Molecularly engineered self-assembling membranes for cell-mediated degradation. Adv Healthc Mater. 2015 Mar 11; 4(4):602-12. View in: PubMed

  87. Overcoming immunological barriers in regenerative medicine. Nat Biotechnol. 2014 Aug; 32(8):786-94. View in: PubMed

  88. Device design and materials optimization of conformal coating for islets of Langerhans. Proc Natl Acad Sci U S A. 2014 Jul 22; 111(29):10514-9. View in: PubMed

  89. Bioluminescent and micro-computed tomography imaging of bone repair induced by fibrin-binding growth factors. Acta Biomater. 2014 Oct; 10(10):4377-89. View in: PubMed

  90. Enhancing efficacy of anticancer vaccines by targeted delivery to tumor-draining lymph nodes. Cancer Immunol Res. 2014 May; 2(5):436-47. View in: PubMed

  91. Long-lasting fibrin matrices ensure stable and functional angiogenesis by highly tunable, sustained delivery of recombinant VEGF164. Proc Natl Acad Sci U S A. 2014 May 13; 111(19):6952-7. View in: PubMed

  92. Clonal, self-renewing and differentiating human and porcine urothelial cells, a novel stem cell population. PLoS One. 2014; 9(2):e90006. View in: PubMed

  93. Growth factors engineered for super-affinity to the extracellular matrix enhance tissue healing. Science. 2014 Feb 21; 343(6173):885-8. View in: PubMed

  94. Culture of preantral follicles in poly(ethylene) glycol-based, three-dimensional hydrogel: a relationship between swelling ratio and follicular developments. J Tissue Eng Regen Med. 2015 Mar; 9(3):319-23. View in: PubMed

  95. Nanoparticle conjugation of CpG enhances adjuvancy for cellular immunity and memory recall at low dose. Proc Natl Acad Sci U S A. 2013 Dec 03; 110(49):19902-7. View in: PubMed

  96. Fibronectin binding modulates CXCL11 activity and facilitates wound healing. PLoS One. 2013; 8(10):e79610. View in: PubMed

  97. Translating materials design to the clinic. Nat Mater. 2013 Nov; 12(11):963-6. View in: PubMed

  98. Targeting the tumor-draining lymph node with adjuvanted nanoparticles reshapes the anti-tumor immune response. Biomaterials. 2014 Jan; 35(2):814-24. View in: PubMed

  99. In situ cell manipulation through enzymatic hydrogel photopatterning. Nat Mater. 2013 Nov; 12(11):1072-8. View in: PubMed

  100. VEGFR-3 neutralization inhibits ovarian lymphangiogenesis, follicle maturation, and murine pregnancy. Am J Pathol. 2013 Nov; 183(5):1596-1607. View in: PubMed

  101. Tissue, cell and engineering. Curr Opin Biotechnol. 2013 Oct; 24(5):827-9. View in: PubMed

  102. Preparation of well-defined ibuprofen prodrug micelles by RAFT polymerization. Biomacromolecules. 2013 Sep 09; 14(9):3314-20. View in: PubMed

  103. Proangiogenic hydrogels within macroporous scaffolds enhance islet engraftment in an extrahepatic site. Tissue Eng Part A. 2013 Dec; 19(23-24):2544-52. View in: PubMed

  104. The promotion of endothelial cell attachment and spreading using FNIII10 fused to VEGF-A165. Biomaterials. 2013 Aug; 34(24):5958-68. View in: PubMed

  105. Proteolytic processing regulates placental growth factor activities. J Biol Chem. 2013 Jun 21; 288(25):17976-89. View in: PubMed

  106. Tenascin C promiscuously binds growth factors via its fifth fibronectin type III-like domain. PLoS One. 2013; 8(4):e62076. View in: PubMed

  107. Peripherally administered nanoparticles target monocytic myeloid cells, secondary lymphoid organs and tumors in mice. PLoS One. 2013; 8(4):e61646. View in: PubMed

  108. Heparin-binding domain of fibrin(ogen) binds growth factors and promotes tissue repair when incorporated within a synthetic matrix. Proc Natl Acad Sci U S A. 2013 Mar 19; 110(12):4563-8. View in: PubMed

  109. Tunable T cell immunity towards a protein antigen using polymersomes vs. solid-core nanoparticles. Biomaterials. 2013 Jun; 34(17):4339-46. View in: PubMed

  110. A high-throughput nanoimmunoassay chip applied to large-scale vaccine adjuvant screening. Integr Biol (Camb). 2013 Apr; 5(4):650-8. View in: PubMed

  111. A feeder-free, defined three-dimensional polyethylene glycol-based extracellular matrix niche for culture of human embryonic stem cells. Biomaterials. 2013 May; 34(14):3571-80. View in: PubMed

  112. Engineering antigens for in situ erythrocyte binding induces T-cell deletion. Proc Natl Acad Sci U S A. 2013 Jan 02; 110(1):E60-8. View in: PubMed

  113. Sorting live stem cells based on Sox2 mRNA expression. PLoS One. 2012; 7(11):e49874. View in: PubMed

  114. Embryonic stem cell-based cardiopatches improve cardiac function in infarcted rats. Stem Cells Transl Med. 2012 Mar; 1(3):248-60. View in: PubMed

  115. Engineering the regenerative microenvironment with biomaterials. Adv Healthc Mater. 2013 Jan; 2(1):57-71. View in: PubMed

  116. Nanoparticle size influences the magnitude and quality of mucosal immune responses after intranasal immunization. Vaccine. 2012 Dec 14; 30(52):7541-6. View in: PubMed

  117. Improving the osteogenic potential of BMP-2 with hyaluronic acid hydrogel modified with integrin-specific fibronectin fragment. Biomaterials. 2013 Jan; 34(3):704-12. View in: PubMed

  118. Long-term maintenance of mouse embryonic stem cell pluripotency by manipulating integrin signaling within 3D scaffolds without active Stat3. Biomaterials. 2012 Dec; 33(35):8934-42. View in: PubMed

  119. Reduction-sensitive tioguanine prodrug micelles. Mol Pharm. 2012 Oct 01; 9(10):2812-8. View in: PubMed

  120. Engineering approaches to immunotherapy. Sci Transl Med. 2012 Aug 22; 4(148):148rv9. View in: PubMed

  121. Precision intracellular delivery based on optofluidic polymersome rupture. ACS Nano. 2012 Sep 25; 6(9):7850-7. View in: PubMed

  122. Chemistry. Nanomaterials for drug delivery. Science. 2012 Jul 20; 337(6092):303-5. View in: PubMed

  123. Investigating the acoustic release of doxorubicin from targeted micelles. Colloids Surf B Biointerfaces. 2013 Jan 01; 101:153-5. View in: PubMed

  124. In-vivo performance of high-density collagen gel tubes for urethral regeneration in a rabbit model. Biomaterials. 2012 Oct; 33(30):7447-55. View in: PubMed

  125. Polymer micelles with pyridyl disulfide-coupled antigen travel through lymphatics and show enhanced cellular responses following immunization. Acta Biomater. 2012 Sep; 8(9):3210-7. View in: PubMed

  126. Dendritic cell activation and T cell priming with adjuvant- and antigen-loaded oxidation-sensitive polymersomes. Biomaterials. 2012 Sep; 33(26):6211-9. View in: PubMed

  127. Size- and charge-dependent non-specific uptake of PEGylated nanoparticles by macrophages. Int J Nanomedicine. 2012; 7:799-813. View in: PubMed

  128. Drug development: longer-lived proteins. Chem Soc Rev. 2012 Apr 07; 41(7):2686-95. View in: PubMed

  129. Twenty-third annual Pezcoller Symposium: engineering influences in cancer research. Cancer Res. 2012 Feb 15; 72(4):841-4. View in: PubMed

  130. Engineered insulin-like growth factor-1 for improved smooth muscle regeneration. Biomaterials. 2012 Jan; 33(2):494-503. View in: PubMed

  131. Nanoparticle conjugation of antigen enhances cytotoxic T-cell responses in pulmonary vaccination. Proc Natl Acad Sci U S A. 2011 Nov 01; 108(44):E989-97. View in: PubMed

  132. PEG-b-PPS-b-PEI micelles and PEG-b-PPS/PEG-b-PPS-b-PEI mixed micelles as non-viral vectors for plasmid DNA: tumor immunotoxicity in B16F10 melanoma. Biomaterials. 2011 Dec; 32(36):9839-47. View in: PubMed

  133. Engineering the growth factor microenvironment with fibronectin domains to promote wound and bone tissue healing. Sci Transl Med. 2011 Sep 14; 3(100):100ra89. View in: PubMed

  134. Toxicity and exposure of an adenovirus containing human interferon alpha-2b following intracystic administration in cynomolgus monkeys. Gene Ther. 2012 Jul; 19(7):742-51. View in: PubMed

  135. Nano-sized drug-loaded micelles deliver payload to lymph node immune cells and prolong allograft survival. J Control Release. 2011 Dec 10; 156(2):154-60. View in: PubMed

  136. Nanoparticle conjugation and pulmonary delivery enhance the protective efficacy of Ag85B and CpG against tuberculosis. Vaccine. 2011 Sep 16; 29(40):6959-66. View in: PubMed

  137. Extracellular matrix in angiogenesis: dynamic structures with translational potential. Exp Dermatol. 2011 Jul; 20(7):605-13. View in: PubMed

  138. A collagen-poly(lactic acid-co-?-caprolactone) hybrid scaffold for bladder tissue regeneration. Biomaterials. 2011 Jun; 32(16):3969-76. View in: PubMed

  139. In situ photopolymerized hydrogels for vascular and peritoneal wound healing. Methods Mol Med. 1999; 18:85-100. View in: PubMed

  140. Enzymatic- and temperature-sensitive controlled release of ultrasmall superparamagnetic iron oxides (USPIOs). J Nanobiotechnology. 2011 Feb 27; 9:7. View in: PubMed

  141. Engineering complement activation on polypropylene sulfide vaccine nanoparticles. Biomaterials. 2011 Mar; 32(8):2194-203. View in: PubMed

  142. Biocompatible dispersions of carbon nanotubes: a potential tool for intracellular transport of anticancer drugs. Nanoscale. 2011 Mar; 3(3):925-8. View in: PubMed

  143. Analytical ultracentrifugation to support the development of biomaterials and biomedical devices. Methods. 2011 May; 54(1):92-100. View in: PubMed

  144. Carbon monoxide-releasing micelles for immunotherapy. J Am Chem Soc. 2010 Dec 29; 132(51):18273-80. View in: PubMed

  145. PPS nanoparticles as versatile delivery system to induce systemic and broad mucosal immunity after intranasal administration. Vaccine. 2011 Jan 17; 29(4):804-12. View in: PubMed

  146. High-density collagen gel tubes as a matrix for primary human bladder smooth muscle cells. Biomaterials. 2011 Feb; 32(6):1543-8. View in: PubMed

  147. SPARC-derived protease substrates to enhance the plasmin sensitivity of molecularly engineered PEG hydrogels. Biomaterials. 2011 Feb; 32(5):1301-10. View in: PubMed

  148. Human embryonic stem cell-derived microvascular grafts for cardiac tissue preservation after myocardial infarction. Biomaterials. 2011 Feb; 32(4):1102-9. View in: PubMed

  149. Drug development: Longer-lived proteins. Nature. 2010 Oct 28; 467(7319):1051-2. View in: PubMed

  150. Antigen delivery to dendritic cells by poly(propylene sulfide) nanoparticles with disulfide conjugated peptides: Cross-presentation and T cell activation. Vaccine. 2010 Nov 23; 28(50):7897-906. View in: PubMed

  151. Engineered aprotinin for improved stability of fibrin biomaterials. Biomaterials. 2011 Jan; 32(2):430-8. View in: PubMed

  152. Improving protein pharmacokinetics by engineering erythrocyte affinity. Mol Pharm. 2010 Dec 06; 7(6):2141-7. View in: PubMed

  153. Dynamic perspective on the function of thermoresponsive nanopores from in situ AFM and ATR-IR investigations. Langmuir. 2010 Oct 05; 26(19):15356-65. View in: PubMed

  154. The effect of matrix characteristics on fibroblast proliferation in 3D gels. Biomaterials. 2010 Nov; 31(32):8454-64. View in: PubMed

  155. The 12th-14th type III repeats of fibronectin function as a highly promiscuous growth factor-binding domain. FASEB J. 2010 Dec; 24(12):4711-21. View in: PubMed

  156. Enhanced proteolytic degradation of molecularly engineered PEG hydrogels in response to MMP-1 and MMP-2. Biomaterials. 2010 Oct; 31(30):7836-45. View in: PubMed

  157. Controlled release nanoparticle-embedded coatings reduce the tissue reaction to neuroprostheses. J Control Release. 2010 Aug 03; 145(3):196-202. View in: PubMed

  158. Synthesis of pyridyl disulfide-functionalized nanoparticles for conjugating thiol-containing small molecules, peptides, and proteins. Bioconjug Chem. 2010 Apr 21; 21(4):653-62. View in: PubMed

  159. In vivo study of an injectable poly(acrylonitrile)-based hydrogel paste as a bulking agent for the treatment of urinary incontinence. Biomaterials. 2010 Jun; 31(17):4613-9. View in: PubMed

  160. Microfluidic assays for DNA manipulation based on a block copolymer immobilization strategy. Biomacromolecules. 2010 Mar 08; 11(3):827-31. View in: PubMed

  161. Integration column: biofunctional polymeric nanoparticles for spatio-temporal control of drug delivery and biomedical applications. Integr Biol (Camb). 2009 Jul; 1(7):446-51. View in: PubMed

  162. In vitro uptake of amphiphilic, hydrogel nanoparticles by J774A.1 cells. J Biomed Mater Res A. 2010 Jun 15; 93(4):1557-65. View in: PubMed

  163. Materials engineering for immunomodulation. Nature. 2009 Nov 26; 462(7272):449-60. View in: PubMed

  164. Engineering integrin signaling for promoting embryonic stem cell self-renewal in a precisely defined niche. Biomaterials. 2010 Feb; 31(6):1219-26. View in: PubMed

  165. A facile strategy for the modification of polyethylene substrates with non-fouling, bioactive poly(poly(ethylene glycol) methacrylate) brushes. Macromol Biosci. 2010 Jan 11; 10(1):101-8. View in: PubMed

  166. Fabrication of nanopore arrays and ultrathin silicon nitride membranes by block-copolymer-assisted lithography. Nanotechnology. 2009 Dec 02; 20(48):485303. View in: PubMed

  167. Compressed collagen gel: a novel scaffold for human bladder cells. J Tissue Eng Regen Med. 2010 Feb; 4(2):123-30. View in: PubMed

  168. Micelles for delivery of nitric oxide. J Am Chem Soc. 2009 Oct 14; 131(40):14413-8. View in: PubMed

  169. Aggregation behavior of poly(ethylene glycol-bl-propylene sulfide) di- and triblock copolymers in aqueous solution. Langmuir. 2009 Oct 06; 25(19):11328-35. View in: PubMed

  170. Biomimetic PEG hydrogels crosslinked with minimal plasmin-sensitive tri-amino acid peptides. J Biomed Mater Res A. 2010 Jun 01; 93(3):870-7. View in: PubMed

  171. A novel method for the encapsulation of biomolecules into polymersomes via direct hydration. Langmuir. 2009 Aug 18; 25(16):9025-9. View in: PubMed


  173. Cell-responsive hydrogel for encapsulation of vascular cells. Biomaterials. 2009 Sep; 30(26):4318-24. View in: PubMed

  174. Porphyrin-based photocatalytic nanolithography: a new fabrication tool for protein arrays. Mol Cell Proteomics. 2009 Aug; 8(8):1823-31. View in: PubMed

  175. Extracellular matrix binding mixed micelles for drug delivery applications. J Control Release. 2009 Jul 20; 137(2):146-51. View in: PubMed

  176. Chemical tethering of motile bacteria to silicon surfaces. Biotechniques. 2009 Mar; 46(3):209-16. View in: PubMed

  177. Bone healing induced by local delivery of an engineered parathyroid hormone prodrug. Biomaterials. 2009 Mar; 30(9):1763-71. View in: PubMed

  178. Phototocatalytic lithography of poly(propylene sulfide) block copolymers: toward high-throughput nanolithography for biomolecular arraying applications. Langmuir. 2009 Jan 20; 25(2):1238-44. View in: PubMed

  179. Controlling integrin specificity and stem cell differentiation in 2D and 3D environments through regulation of fibronectin domain stability. Biomaterials. 2009 Feb; 30(6):1089-97. View in: PubMed

  180. Superparamagnetic nanoparticles as a powerful systems biology characterization tool in the physiological context. Angew Chem Int Ed Engl. 2008; 47(41):7857-60. View in: PubMed

  181. Cellular matrices: Physiology in microfluidics. Nat Mater. 2008 Aug; 7(8):609-10. View in: PubMed

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