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Bana Jabri

Professor
bjabri@uchicago.edu
Biosciences Graduate Program Association
Publications

  1. GATA4 controls regionalization of tissue immunity and commensal-driven immunopathology. Immunity. 2023 01 10; 56(1):43-57.e10. View in: PubMed

  2. LRP-1 links post-translational modifications to efficient presentation of celiac disease-specific T?cell antigens. Cell Chem Biol. 2023 Jan 19; 30(1):55-68.e10. View in: PubMed

  3. Paired bone marrow and peripheral blood samples demonstrate lack of widespread dissemination of some CH clones. Blood Adv. 2023 May 09; 7(9):1910-1914. View in: PubMed

  4. Maladaptive consequences of inflammatory events shape individual immune identity. Nat Immunol. 2022 Nov 21. View in: PubMed

  5. Nociceptor neurons direct goblet cells via a CGRP-RAMP1 axis to drive mucus production and gut barrier protection. Cell. 2022 10 27; 185(22):4190-4205.e25. View in: PubMed

  6. A Mouse Model of Celiac Disease. Curr Protoc. 2022 Aug; 2(8):e515. View in: PubMed

  7. NK cells contribute to reovirus-induced IFN responses and loss of tolerance to dietary antigen. JCI Insight. 2022 08 22; 7(16). View in: PubMed

  8. Innate riddle of CD4+ T?cells and the control of enteric infections. Immunity. 2022 07 12; 55(7):1145-1147. View in: PubMed

  9. Tet2 deficiency drives liver microbiome dysbiosis triggering Tc1 cell autoimmune hepatitis. Cell Host Microbe. 2022 07 13; 30(7):1003-1019.e10. View in: PubMed

  10. An efficient urine peptidomics workflow identifies chemically defined dietary gluten peptides from patients with celiac disease. Nat Commun. 2022 02 16; 13(1):888. View in: PubMed

  11. High molecular weight DNA extraction strategies for long-read sequencing of complex metagenomes. Mol Ecol Resour. 2022 Jul; 22(5):1786-1802. View in: PubMed

  12. Candida albicans and Candida dubliniensis in Periodontitis in Adolescents and Young Adults. Int J Microbiol. 2022; 2022:4625368. View in: PubMed

  13. A multilayered immune system through the lens of unconventional T cells. Nature. 2021 07; 595(7868):501-510. View in: PubMed

  14. Transglutaminase 2 Inhibition for Prevention of Mucosal Damage in Celiac Disease. N Engl J Med. 2021 07 01; 385(1):76-77. View in: PubMed

  15. High-sensitivity C-reactive protein is associated with clonal hematopoiesis of indeterminate potential. Blood Adv. 2020 06 09; 4(11):2430-2438. View in: PubMed

  16. Fecal microbiota transplant rescues mice from human pathogen mediated sepsis by restoring systemic immunity. Nat Commun. 2020 05 11; 11(1):2354. View in: PubMed

  17. IL-15, gluten and HLA-DQ8 drive tissue destruction in coeliac disease. Nature. 2020 02; 578(7796):600-604. View in: PubMed

  18. Tissue alarmins and adaptive cytokine induce dynamic and distinct transcriptional responses in tissue-resident intraepithelial cytotoxic T lymphocytes. J Autoimmun. 2020 03; 108:102422. View in: PubMed

  19. Identification of a ?c Receptor Antagonist That Prevents Reprogramming of Human Tissue-resident Cytotoxic T Cells by IL15 and IL21. Gastroenterology. 2020 02; 158(3):625-637.e13. View in: PubMed

  20. Cytokine release and gastrointestinal symptoms after gluten challenge in celiac disease. Sci Adv. 2019 08; 5(8):eaaw7756. View in: PubMed

  21. Duodenal bacterial proteolytic activity determines sensitivity to dietary antigen through protease-activated receptor-2. Nat Commun. 2019 03 13; 10(1):1198. View in: PubMed

  22. Chronic Inflammation Permanently Reshapes Tissue-Resident Immunity in Celiac Disease. Cell. 2019 02 21; 176(5):967-981.e19. View in: PubMed

  23. Murine Norovirus Infection Induces TH1 Inflammatory Responses to Dietary Antigens. Cell Host Microbe. 2018 11 14; 24(5):677-688.e5. View in: PubMed

  24. Single-Cell RNA Sequencing of Blood and Ileal T Cells From Patients With Crohn's Disease Reveals Tissue-Specific Characteristics and Drug Targets. Gastroenterology. 2019 02; 156(3):812-815.e22. View in: PubMed

  25. A viral trigger for celiac disease. PLoS Pathog. 2018 09; 14(9):e1007181. View in: PubMed

  26. Mechanisms by which gut microorganisms influence food sensitivities. Nat Rev Gastroenterol Hepatol. 2019 01; 16(1):7-18. View in: PubMed

  27. Data on changes to mucosal inflammation and the intestinal microbiota following dietary micronutrients in genetically susceptible hosts. Data Brief. 2018 Oct; 20:387-393. View in: PubMed

  28. P31-43, an undigested gliadin peptide, mimics and enhances the innate immune response to viruses and interferes with endocytic trafficking: a role in celiac disease. Sci Rep. 2018 Jul 17; 8(1):10821. View in: PubMed

  29. Mitochondria maintain controlled activation state of epithelial-resident T lymphocytes. Sci Immunol. 2018 06 22; 3(24). View in: PubMed

  30. Epithelial IL-15 Is a Critical Regulator of ?d Intraepithelial Lymphocyte Motility within the Intestinal Mucosa. J Immunol. 2018 07 15; 201(2):747-756. View in: PubMed

  31. A locus at 7p14.3 predisposes to refractory celiac disease progression from celiac disease. Eur J Gastroenterol Hepatol. 2018 08; 30(8):828-837. View in: PubMed

  32. Microbial signals drive pre-leukaemic myeloproliferation in a Tet2-deficient host. Nature. 2018 05; 557(7706):580-584. View in: PubMed

  33. Diverse developmental pathways of intestinal intraepithelial lymphocytes. Nat Rev Immunol. 2018 08; 18(8):514-525. View in: PubMed

  34. Human intraepithelial lymphocytes. Mucosal Immunol. 2018 09; 11(5):1281-1289. View in: PubMed

  35. Reovirus-Induced Apoptosis in the Intestine Limits Establishment of Enteric Infection. J Virol. 2018 05 15; 92(10). View in: PubMed

  36. Dietary antioxidant micronutrients alter mucosal inflammatory risk in a murine model of genetic and microbial susceptibility. J Nutr Biochem. 2018 04; 54:95-104. View in: PubMed

  37. Natural polyreactive IgA antibodies coat the intestinal microbiota. Science. 2017 10 20; 358(6361). View in: PubMed

  38. Antibiotic-induced perturbations in microbial diversity during post-natal development alters amyloid pathology in an aged APPSWE/PS1?E9 murine model of Alzheimer's disease. Sci Rep. 2017 09 05; 7(1):10411. View in: PubMed

  39. Patients With Ulcerative Colitis and Primary Sclerosing Cholangitis Frequently Have Subclinical Inflammation in?the?Proximal Colon. Clin Gastroenterol Hepatol. 2018 Jan; 16(1):68-74. View in: PubMed

  40. Human Leukocyte Antigen F Presents Peptides and Regulates Immunity through Interactions with NK Cell Receptors. Immunity. 2017 06 20; 46(6):1018-1029.e7. View in: PubMed

  41. Epitope-specific immunotherapy targeting CD4-positive T cells in coeliac disease: two randomised, double-blind, placebo-controlled phase 1 studies. Lancet Gastroenterol Hepatol. 2017 07; 2(7):479-493. View in: PubMed

  42. Reovirus infection triggers inflammatory responses to dietary antigens and development of celiac disease. Science. 2017 04 07; 356(6333):44-50. View in: PubMed

  43. T Cells in Celiac Disease. J Immunol. 2017 04 15; 198(8):3005-3014. View in: PubMed

  44. Open-Capsule Budesonide for Refractory Celiac Disease. Am J Gastroenterol. 2017 Jun; 112(6):959-967. View in: PubMed

  45. Early Transcriptomic Changes in the Ileal Pouch Provide Insight into the Molecular Pathogenesis of Pouchitis and Ulcerative Colitis. Inflamm Bowel Dis. 2017 Feb 13. View in: PubMed

  46. Early Transcriptomic Changes in the Ileal Pouch Provide Insight into the Molecular Pathogenesis of Pouchitis and Ulcerative Colitis. Inflamm Bowel Dis. 2017 03; 23(3):366-378. View in: PubMed

  47. Interleukin-15 promotes intestinal dysbiosis with butyrate deficiency associated with increased susceptibility to colitis. ISME J. 2017 01; 11(1):15-30. View in: PubMed

  48. Butyrate and bioactive proteolytic form of Wnt-5a regulate colonic epithelial proliferation and spatial development. Sci Rep. 2016 08 26; 6:32094. View in: PubMed

  49. A dendritic cell subset designed for oral tolerance. Nat Immunol. 2016 May; 17(5):474-6. View in: PubMed

  50. The features of mucosa-associated microbiota in primary sclerosing cholangitis. Aliment Pharmacol Ther. 2016 Apr; 43(7):790-801. View in: PubMed

  51. IL-15 functions as a danger signal to regulate tissue-resident T cells and tissue destruction. Nat Rev Immunol. 2015 12; 15(12):771-83. View in: PubMed

  52. IMMUNOLOGY. Breaching the gut-vascular barrier. Science. 2015 Nov 13; 350(6262):742-3. View in: PubMed

  53. Commensal Bifidobacterium promotes antitumor immunity and facilitates anti-PD-L1 efficacy. Science. 2015 Nov 27; 350(6264):1084-9. View in: PubMed

  54. Intestinal microbiota modulates gluten-induced immunopathology in humanized mice. Am J Pathol. 2015 Nov; 185(11):2969-82. View in: PubMed

  55. Innate and Adaptive Humoral Responses Coat Distinct Commensal Bacteria with Immunoglobulin A. Immunity. 2015 Sep 15; 43(3):541-53. View in: PubMed

  56. Cysteinyl leukotrienes mediate lymphokine killer activity induced by NKG2D and IL-15 in cytotoxic T cells during celiac disease. J Exp Med. 2015 Sep 21; 212(10):1487-95. View in: PubMed

  57. Innate immunity: actuating the gears of celiac disease pathogenesis. Best Pract Res Clin Gastroenterol. 2015 Jun; 29(3):425-35. View in: PubMed

  58. Novel players in coeliac disease pathogenesis: role of the gut microbiota. Nat Rev Gastroenterol Hepatol. 2015 Sep; 12(9):497-506. View in: PubMed

  59. Distinct and Synergistic Contributions of Epithelial Stress and Adaptive Immunity to Functions of Intraepithelial Killer Cells and Active Celiac Disease. Gastroenterology. 2015 Sep; 149(3):681-91.e10. View in: PubMed

  60. Editorial overview: Autoimmunity. Curr Opin Immunol. 2014 Dec; 31:v-vii. View in: PubMed

  61. Elevated T cell receptor signaling identifies a thymic precursor to the TCRa?(+)CD4(-)CD8?(-) intraepithelial lymphocyte lineage. Immunity. 2014 Aug 21; 41(2):219-29. View in: PubMed

  62. Isotretinoin use and celiac disease: a population-based cross-sectional study. Am J Clin Dermatol. 2014 Dec; 15(6):537-42. View in: PubMed

  63. IL-15: a central regulator of celiac disease immunopathology. Immunol Rev. 2014 Jul; 260(1):221-34. View in: PubMed

  64. Human NKG2E is expressed and forms an intracytoplasmic complex with CD94 and DAP12. J Immunol. 2014 Jul 15; 193(2):610-6. View in: PubMed

  65. How T cells taste gluten in celiac disease. Nat Struct Mol Biol. 2014 May; 21(5):429-31. View in: PubMed

  66. Phosphate-containing polyethylene glycol polymers prevent lethal sepsis by multidrug-resistant pathogens. Antimicrob Agents Chemother. 2014; 58(2):966-77. View in: PubMed

  67. Crystal structure of Vd1 T cell receptor in complex with CD1d-sulfatide shows MHC-like recognition of a self-lipid by human ?d T cells. Immunity. 2013 Dec 12; 39(6):1032-42. View in: PubMed

  68. Interleukin 15 primes natural killer cells to kill via NKG2D and cPLA2 and this pathway is active in psoriatic arthritis. PLoS One. 2013; 8(9):e76292. View in: PubMed

  69. Insulin-dependent diabetes induced by pancreatic beta cell expression of IL-15 and IL-15Ra. Proc Natl Acad Sci U S A. 2013 Aug 13; 110(33):13534-9. View in: PubMed

  70. IL-15 in tumor microenvironment causes rejection of large established tumors by T cells in a noncognate T cell receptor-dependent manner. Proc Natl Acad Sci U S A. 2013 May 14; 110(20):8158-63. View in: PubMed

  71. Triggers and drivers of autoimmunity: lessons from coeliac disease. Nat Rev Immunol. 2013 04; 13(4):294-302. View in: PubMed

  72. Vaccine against autoimmune disease: antigen-specific immunotherapy. Curr Opin Immunol. 2013 Jun; 25(3):410-7. View in: PubMed

  73. Pathophysiology of celiac disease. Gastrointest Endosc Clin N Am. 2012 Oct; 22(4):639-60. View in: PubMed

  74. The majority of CD1d-sulfatide-specific T cells in human blood use a semiinvariant Vd1 TCR. Eur J Immunol. 2012 Sep; 42(9):2505-10. View in: PubMed

  75. A specific role for TLR1 in protective T(H)17 immunity during mucosal infection. J Exp Med. 2012 Jul 30; 209(8):1437-44. View in: PubMed

  76. Dietary-fat-induced taurocholic acid promotes pathobiont expansion and colitis in Il10-/- mice. Nature. 2012 Jul 05; 487(7405):104-8. View in: PubMed

  77. Intraepithelial lymphocytes in celiac disease immunopathology. Semin Immunopathol. 2012 Jul; 34(4):551-66. View in: PubMed

  78. Densely granulated murine NK cells eradicate large solid tumors. Cancer Res. 2012 Apr 15; 72(8):1964-74. View in: PubMed

  79. Don't move: LRRK2 arrests NFAT in the cytoplasm. Nat Immunol. 2011 Oct 19; 12(11):1029-30. View in: PubMed

  80. Celiac disease and transglutaminase 2: a model for posttranslational modification of antigens and HLA association in the pathogenesis of autoimmune disorders. Curr Opin Immunol. 2011 Dec; 23(6):732-8. View in: PubMed

  81. Potential celiac patients: a model of celiac disease pathogenesis. PLoS One. 2011; 6(7):e21281. View in: PubMed

  82. The Toll-like receptor 2 pathway establishes colonization by a commensal of the human microbiota. Science. 2011 May 20; 332(6032):974-7. View in: PubMed

  83. Coeliac disease and gluten sensitivity. J Intern Med. 2011 Jun; 269(6):582-90. View in: PubMed

  84. Co-adjuvant effects of retinoic acid and IL-15 induce inflammatory immunity to dietary antigens. Nature. 2011 Mar 10; 471(7337):220-4. View in: PubMed

  85. Integration of genetic and immunological insights into a model of celiac disease pathogenesis. Annu Rev Immunol. 2011; 29:493-525. View in: PubMed

  86. Regional mucosa-associated microbiota determine physiological expression of TLR2 and TLR4 in murine colon. PLoS One. 2010 Oct 22; 5(10):e13607. View in: PubMed

  87. NKG2D initiates caspase-mediated CD3zeta degradation and lymphocyte receptor impairments associated with human cancer and autoimmune disease. J Immunol. 2010 Nov 15; 185(10):5732-42. View in: PubMed

  88. Regional differences in colonic mucosa-associated microbiota determine the physiological expression of host heat shock proteins. Am J Physiol Gastrointest Liver Physiol. 2010 Dec; 299(6):G1266-75. View in: PubMed

  89. The diabetogenic mouse MHC class II molecule I-Ag7 is endowed with a switch that modulates TCR affinity. J Clin Invest. 2010 May; 120(5):1578-90. View in: PubMed

  90. Tissue-mediated control of immunopathology in coeliac disease. Nat Rev Immunol. 2009 Dec; 9(12):858-70. View in: PubMed

  91. Cytosolic PLA2 is required for CTL-mediated immunopathology of celiac disease via NKG2D and IL-15. J Exp Med. 2009 Mar 16; 206(3):707-19. View in: PubMed

  92. The role of HLA-DQ8 beta57 polymorphism in the anti-gluten T-cell response in coeliac disease. Nature. 2008 Nov 27; 456(7221):534-8. View in: PubMed

  93. Toll-like receptor 6 drives differentiation of tolerogenic dendritic cells and contributes to LcrV-mediated plague pathogenesis. Cell Host Microbe. 2008 Oct 16; 4(4):350-61. View in: PubMed

  94. Massive interleukin-12-induced interferon-gamma production by interleukin-15-stimulated lamina propria lymphocytes followed by down-regulation of the interleukin-12 receptor. Immunology. 2008 Aug; 124(4):453-60. View in: PubMed

  95. Extracellular transglutaminase 2 is catalytically inactive, but is transiently activated upon tissue injury. PLoS One. 2008 Mar 26; 3(3):e1861. View in: PubMed

  96. Small intestinal CD8+TCRgammadelta+NKG2A+ intraepithelial lymphocytes have attributes of regulatory cells in patients with celiac disease. J Clin Invest. 2008 Jan; 118(1):281-93. View in: PubMed

  97. The Bacillus subtilis quorum-sensing molecule CSF contributes to intestinal homeostasis via OCTN2, a host cell membrane transporter. Cell Host Microbe. 2007 Jun 14; 1(4):299-308. View in: PubMed

  98. Gliadin regulates the NK-dendritic cell cross-talk by HLA-E surface stabilization. J Immunol. 2007 Jul 01; 179(1):372-81. View in: PubMed

  99. Human CD8+ intraepithelial lymphocytes: a unique model to study the regulation of effector cytotoxic T lymphocytes in tissue. Immunol Rev. 2007 Feb; 215:202-14. View in: PubMed

  100. Expression of nonclassical class I molecules by intestinal epithelial cells. Inflamm Bowel Dis. 2007 Mar; 13(3):298-307. View in: PubMed

  101. Mechanisms of disease: immunopathogenesis of celiac disease. Nat Clin Pract Gastroenterol Hepatol. 2006 Sep; 3(9):516-25. View in: PubMed

  102. Immunogenicity and protective immunity against bubonic plague and pneumonic plague by immunization of mice with the recombinant V10 antigen, a variant of LcrV. Infect Immun. 2006 Aug; 74(8):4910-4. View in: PubMed

  103. Reprogramming of CTLs into natural killer-like cells in celiac disease. J Exp Med. 2006 May 15; 203(5):1343-55. View in: PubMed

  104. Celiac disease. Annu Rev Med. 2006; 57:207-21. View in: PubMed

  105. NKG2 receptor-mediated regulation of effector CTL functions in the human tissue microenvironment. Curr Top Microbiol Immunol. 2006; 298:139-56. View in: PubMed

  106. Is celiac disease an autoimmune disorder? Curr Opin Immunol. 2005 Dec; 17(6):595-600. View in: PubMed

  107. Plague bacteria target immune cells during infection. Science. 2005 Sep 09; 309(5741):1739-41. View in: PubMed

  108. Innate and adaptive immunity: the yin and yang of celiac disease. Immunol Rev. 2005 Aug; 206:219-31. View in: PubMed

  109. LcrV plague vaccine with altered immunomodulatory properties. Infect Immun. 2005 Aug; 73(8):5152-9. View in: PubMed

  110. Relationship of HLA-DQ8 and severity of celiac disease: comparison of New York and Parisian cohorts. Clin Gastroenterol Hepatol. 2004 Oct; 2(10):888-94. View in: PubMed

  111. Coordinated induction by IL15 of a TCR-independent NKG2D signaling pathway converts CTL into lymphokine-activated killer cells in celiac disease. Immunity. 2004 Sep; 21(3):357-66. View in: PubMed

  112. Risk of malignancy in patients with celiac disease. Am J Med. 2003 Aug 15; 115(3):191-5. View in: PubMed

  113. Coeliac disease. Lancet. 2003 Aug 02; 362(9381):383-91. View in: PubMed

  114. TCR specificity dictates CD94/NKG2A expression by human CTL. Immunity. 2002 Oct; 17(4):487-99. View in: PubMed

  115. Celiac disease and other precursors to small-bowel malignancy. Gastroenterol Clin North Am. 2002 Jun; 31(2):625-39. View in: PubMed

  116. NKG2D receptors induced by IL-15 costimulate CD28-negative effector CTL in the tissue microenvironment. J Immunol. 2001 Nov 15; 167(10):5527-30. View in: PubMed

  117. Refractory sprue, coeliac disease, and enteropathy-associated T-cell lymphoma. French Coeliac Disease Study Group. Lancet. 2000 Jul 15; 356(9225):203-8. View in: PubMed

  118. Distinction between coeliac disease and refractory sprue: a simple immunohistochemical method. Histopathology. 2000 Jul; 37(1):70-7. View in: PubMed

  119. Selective expansion of intraepithelial lymphocytes expressing the HLA-E-specific natural killer receptor CD94 in celiac disease. Gastroenterology. 2000 May; 118(5):867-79. View in: PubMed

  120. Selection and expansion of CD8alpha/alpha(1) T cell receptor alpha/beta(1) intestinal intraepithelial lymphocytes in the absence of both classical major histocompatibility complex class I and nonclassical CD1 molecules. J Exp Med. 1999 Sep 20; 190(6):885-90. View in: PubMed

  121. syk protein tyrosine kinase regulates Fc receptor gamma-chain-mediated transport to lysosomes. EMBO J. 1998 Aug 17; 17(16):4606-16. View in: PubMed

  122. Small bowel transplantation alone or with the liver in children: changes by using FK506. Transplant Proc. 1998 Jun; 30(4):1569-70. View in: PubMed

  123. Abnormal intestinal intraepithelial lymphocytes in refractory sprue. Gastroenterology. 1998 Mar; 114(3):471-81. View in: PubMed
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