Jeffrey Hubbell

Blocking antibodies against integrin-a3, -aM, and -aMß2 de-differentiate myofibroblasts, and improve lung fibrosis and kidney fibrosis.
Blocking antibodies against integrin-a3, -aM, and -aMß2 de-differentiate myofibroblasts, and improve lung fibrosis and kidney fibrosis. Sci Rep. 2024 09 16; 14(1):21623.
PMID: 39284829

Semaphorin 3A promotes the long-term persistence of human SVF-derived microvascular networks in engineered grafts.
Semaphorin 3A promotes the long-term persistence of human SVF-derived microvascular networks in engineered grafts. Front Bioeng Biotechnol. 2024; 12:1396450.
PMID: 39234267

Injectable butyrate-prodrug micelles induce long-acting immune modulation and prevent autoimmune arthritis in mice.
Injectable butyrate-prodrug micelles induce long-acting immune modulation and prevent autoimmune arthritis in mice. J Control Release. 2024 Aug; 372:281-294.
PMID: 38876359

Cysteine-binding adjuvant enhances survival and promotes immune function in a murine model of acute myeloid leukemia.
Cysteine-binding adjuvant enhances survival and promotes immune function in a murine model of acute myeloid leukemia. Blood Adv. 2024 04 09; 8(7):1747-1759.
PMID: 38324726

A serine-conjugated butyrate prodrug with high oral bioavailability suppresses autoimmune arthritis and neuroinflammation in mice.
A serine-conjugated butyrate prodrug with high oral bioavailability suppresses autoimmune arthritis and neuroinflammation in mice. Nat Biomed Eng. 2024 May; 8(5):611-627.
PMID: 38561491

LDL-Binding IL-10 Reduces Vascular Inflammation in Atherosclerotic Mice.
LDL-Binding IL-10 Reduces Vascular Inflammation in Atherosclerotic Mice. bioRxiv. 2024 Mar 06.
PMID: 38496521

Therapeutic synthetic and natural materials for immunoengineering.
Therapeutic synthetic and natural materials for immunoengineering. Chem Soc Rev. 2024 Feb 19; 53(4):1789-1822.
PMID: 38170619

Immunoengineering a Future of Molecular, Material, and Cellular Therapeutics.
Immunoengineering a Future of Molecular, Material, and Cellular Therapeutics. J Immunol. 2024 01 15; 212(2):167-168.
PMID: 38166250

Synthetically mannosylated antigens induce antigen-specific humoral tolerance and reduce anti-drug antibody responses to immunogenic biologics.
Synthetically mannosylated antigens induce antigen-specific humoral tolerance and reduce anti-drug antibody responses to immunogenic biologics. Cell Rep Med. 2024 01 16; 5(1):101345.
PMID: 38128533

Glycosylation-modified antigens as a tolerance-inducing vaccine platform prevent anaphylaxis in a pre-clinical model of food allergy.
Glycosylation-modified antigens as a tolerance-inducing vaccine platform prevent anaphylaxis in a pre-clinical model of food allergy. Cell Rep Med. 2024 01 16; 5(1):101346.
PMID: 38128531

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